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Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models

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  1. Article

    Open Access

    Radiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma by inducing active transformation of tumor-infiltrating CD8+ T and NK cells

    Immunosuppression by the tumor microenvironment is a pivotal factor contributing to tumor progression and immunotherapy resistance. Priming the tumor immune microenvironment (TIME) has emerged as a promising s...

    Jia-zheng Jiao, Yang Zhang, Wen-juan Zhang, Min-di He in Acta Pharmacologica Sinica (2024)

  2. Article

    Open Access

    Colonization with ubiquitous protist Blastocystis ST1 ameliorates DSS-induced colitis and promotes beneficial microbiota and immune outcomes

    Blastocystis is a species complex that exhibits extensive genetic diversity, evidenced by its classification into several genetically distinct subtypes (ST). Although several studies have shown the relationships ...

    Lei Deng, Lukasz Wojciech, Chin Wen Png in npj Biofilms and Microbiomes (2023)

  3. Article

    Fungal diversity notes 1512–1610: taxonomic and phylogenetic contributions on genera and species of fungal taxa

    This article is the 14th in the Fungal Diversity Notes series, wherein we report 98 taxa distributed in two phyla, seven classes, 26 orders and 50 families which are described and illustrated. Taxa in this stu...

    Ruvishika S. Jayawardena, Kevin D. Hyde, Song Wang, Ya-Ru Sun in Fungal Diversity (2022)

  4. Article

    Open Access

    Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study

    Streptococcus pneumoniae (S. pneumoniae) is a major cause of bacterial meningitis, septicemia and pneumonia in children. Inappropriate choice of antibiotic can have important adverse consequences for both the ind...

    Tian-ming Chen, Wen-hui Li, Fang Wang, Kun Tan, Qing-xiong Zhu in BMC Infectious Diseases (2021)

  5. Article

    Fungal diversity notes 1387–1511: taxonomic and phylogenetic contributions on genera and species of fungal taxa

    This article is the 13th contribution in the Fungal Diversity Notes series, wherein 125 taxa from four phyla, ten classes, 31 orders, 69 families, 92 genera and three genera incertae sedis are treated, demonstrat...

    Saranyaphat Boonmee, Dhanushka N. Wanasinghe, Mark S. Calabon in Fungal Diversity (2021)

  6. Article

    Taxonomy of the order Bunyavirales: update 2019

    In February 2019, following the annual taxon ratification vote, the order Bunyavirales was amended by creation of two new families, four new subfamilies, 11 new genera and 77 new species, merging of two species, ...

    Abulikemu Abudurexiti, Scott Adkins, Daniela Alioto in Archives of Virology (2019)

  7. Article

    Open Access

    MicroRNA expression profile in exosome discriminates extremely severe infections from mild infections for hand, foot and mouth disease

    Changes of miRNAs in exosome have been reported in different disease diagnosis and provided as potential biomarkers. In this study, we compared microRNA profile in exosomes in 5 MHFMD and 5 ESHFMD as well as i...

    Hong-Ling Jia, Chun-Hui He, Zhuo-Ya Wang, Yu-Fen Xu in BMC Infectious Diseases (2014)

  8. Article

    Open Access

    Proteomic analysis of extremely severe hand, foot and mouth disease infected by enterovirus 71

    To clarify the molecular mechanisms that participate in the severe hand, foot and mouth disease (HFMD) infected by Enterovirus 71 and to detect any related protein biomarkers, we performed proteomic analysis o...

    Li Deng, Hong-Ling Jia, Chao-Wu Liu, Yu-Fen Xu, Li-Jia Mao in BMC Infectious Diseases (2013)

  9. Article

    Curcumin downregulates homeobox gene NKX3.1 in prostate cancer cell LNCaP

    To elucidate the effect and the mechanisms of curcumin on the expression of the human homeobox gene NKX3.1 in the prostate cancer cell LNCaP.

    Hui-na Zhang, Chun-xiao Yu, Peng-ju Zhang, Wei-wen Chen in Acta Pharmacologica Sinica (2007)

  10. Article

    Multiple dose pharmacokinetics of risperidone and 9-hydroxyrisperidone in Chinese female patients with schizophrenia

    To study the multiple dose clinical pharmacokinetics of risperidone and its main active metabolite, 9-hydroxyrisperidone, in Chinese female patients with schizophrenia.

    Zhi-ling Zhou, **n Li, Huai-yan Peng, **-yong Yu, Ming Yang in Acta Pharmacologica Sinica (2006)