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Article
Open AccessWhat are the differences in paraspinal muscle morphometry among degenerative spondylolisthesis patients, isthmic spondylolisthesis patients, and healthy individuals? A propensity score matching analysis
To compare the morphometry of paraspinal muscles in patients with degenerative spondylolisthesis (DS), isthmic spondylolisthesis (IS), and healthy individuals.
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Article
Open AccessEvaluation of models to predict prognosis in patients with advanced hepatocellular carcinoma treated with TACE combined with apatinib
The HAP, Six-and-Twelve, Up to Seven, and ALBI scores have been substantiated as reliable prognostic markers in patients presenting with intermediate and advanced hepatocellular carcinoma (HCC) undergoing tran...
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Article
Open AccessMETTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation
While liver cancer stem cells (CSCs) play a crucial role in hepatocellular carcinoma (HCC) initiation, progression, recurrence, and treatment resistance, the mechanism underlying liver CSC self-renewal remains...
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Article
A comprehensive analysis of the association between anemia and systemic inflammation in older patients with cancer
Our study aimed to comprehensively analyze the association between anemia and systemic inflammation in older patients with cancer.
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Article
Ethyl Lithospermate Reduces Lipopolysaccharide-Induced Inflammation through Inhibiting NF-κB and STAT3 Pathways in RAW 264.7 Cells and Zebrafish
To explore the anti-inflammatory effects of ethyl lithospermate in lipopolysaccharide (LPS)-stimulated RAW 264.7 murine-derived macrophages and zebrafish, and its underlying mechanisms.
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Article
The Incidence of Long-Term Cholangitis after Endoscopic Papillary Balloon Dilation Versus Endoscopic Sphincterotomy: a Meta-analysis
The objective of this study was to assess the long-term incidence of cholangitis after endoscopic papillary balloon dilation (EPBD) and endoscopic sphincterotomy (EST) using a meta-analysis. Until December, 20...
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Article
Open AccessImmune checkpoint inhibitors combined with or without radio(chemo)therapy for locally advanced or recurrent/metastatic esophageal squamous cell carcinoma
This study was designed to investigate the efficacy and prognostic factors for immune checkpoint inhibitors (ICIs) combined with or without radio(chemo)therapy and to evaluate their toxicity in patients with l...
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Article
Open AccessInitiation and duration of folic acid supplementation in preventing congenital malformations
Folic acid (FA) supplementation is associated with a lower risk of the neural tube and heart defects and is recommended for women of childbearing age. Although there are detailed recommendations, differences i...
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Article
Open AccessEffect of intraoperative remimazolam on postoperative sleep quality in elderly patients after total joint arthroplasty: a randomized control trial
To investigate the effect of intraoperative remimazolam sedation on postoperative sleep quality in elderly patients after total joint arthroplasty.
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Article
Open AccessThe Presence of Diabetes Mellitus or Pre-diabetes Mellitus Increases Mortality from Heart Disease in a Taiwanese Population: A 10-year Follow-Up Study
We evaluated hyperglycemia-associated mortality in the Taiwanese population by conducting a 10-year retrospective cohort study. Methods: From 2007 to 2017, all participants, regardless of their age or underlyi...
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Article
Open AccessOTUB1 promotes osteoblastic bone formation through stabilizing FGFR2
Bone homeostasis is maintained by the balance between osteoblastic bone formation and osteoclastic bone resorption. Dysregulation of this process leads to multiple diseases, including osteoporosis. However, th...
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Article
Open AccessParental hesitancy against COVID-19 vaccination for children and associated factors in Taiwan
Since July 2021, some countries and regions have initiated the vaccination of minors against coronavirus disease (COVID-19), and parental COVID-19 vaccine hesitancy will affect the vaccination of minors. We ai...
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Article
Open AccessThe development of a cSMART-based integrated model for hepatocellular carcinoma diagnosis
Hepatocellular carcinoma (HCC) generally arises from a background of liver cirrhosis (LC). Patients with cirrhosis and suspected HCC are recommended to undergo serum biomarker tests and imaging diagnostic eval...
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Chapter
Inflammatory Disorders of the Small Intestines
Ulcerative and erosive disease in the small intestine are the another group of entities that cause small bowel bleeding, stricture, obstruction and even perforation. In this chapter, authors presented various ...
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Chapter
Extensively Drug-Resistant Tuberculosis
Extensively drug-resistant tuberculosis (XDR-TB) is defined as a tuberculosis of MDR/RR-TB plus resistant simultaneously to any one of fluoroquinolones and at least any one of bedaquiline and linezolid.
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Article
Open AccessAccuracy of calculating mechanical power of ventilation by one commonly used equation
Gattinoni’s equation, $${\text{MP}}_{{{\text{rs}}}} \, = \,0.098\, \times \,{\text{RR}}\, \times \,\left[ {{\text{V}}_{T} ^{2} \left( {\frac{1...
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Article
Naoxintong Capsule for Secondary Prevention of Ischemic Stroke: A Multicenter, Randomized, and Placebo-Controlled Trial
To examine whether the combination of Naoxintong Capsule with standard care could further reduce the recurrence of ischemic stroke without increasing the risk of severe bleeding.
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Article
Cardiac magnetic resonance T1 map** for evaluating myocardial fibrosis in patients with type 2 diabetes mellitus: correlation with left ventricular longitudinal diastolic dysfunction
We aimed to evaluate myocardial fibrosis using cardiac magnetic resonance (CMR) T1 map** in type 2 diabetes mellitus (T2DM) patients and investigate the association between left ventricular (LV) subclinical ...
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Article
Intracranial drainage versus extracranial shunt in the treatment of intracranial arachnoid cysts: a meta-analysis
To review the literature and analyze the efficacy and safety of two surgery procedures, intracranial drainage and extracranial shunt, for intracranial arachnoid cysts.
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Article
Open AccessComprehensive analysis of CXCR family members in lung adenocarcinoma with prognostic values
The expression profiles and molecular mechanisms of CXC chemokine receptors (CXCRs) in Lung adenocarcinoma (LUAD) have been extensively explored. However, the comprehensive prognostic values of CXCR members in...