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  1. Article

    Open Access

    Long-term ozone exposure and mortality in patients with chronic kidney disease: a large cohort study

    Epidemiologic studies on the effects of long-term exposure to ozone (O3) have shown inconclusive results. It is unclear whether to O3 has an effect on chronic kidney disease (CKD). We investigated the effects of ...

    E** Kim, Hyuk Huh, Yongwon Mo, Jae Yoon Park, Jiyun Jung, Hajeong Lee in BMC Nephrology (2024)

  2. No Access

    Article

    Causal effects from tobacco smoking initiation on obesity-related traits: a Mendelian randomization study

    There is a widespread notion that tobacco smoking controls weight based on the appetite suppressive effect of nicotine. However, the causal relationship between smoking initiation and obesity-related traits in...

    Sehoon Park, Seong Geun Kim, Soo** Lee, Yaerim Kim in International Journal of Obesity (2023)

  3. Article

    Open Access

    Nonlinear causal effects of estimated glomerular filtration rate on myocardial infarction risks: Mendelian randomization study

    Previous observational studies suggested that a reduction in estimated glomerular filtration rate (eGFR) or a supranormal eGFR value was associated with adverse cardiovascular risks. However, a previous Mendel...

    Sehoon Park, Soo** Lee, Yaerim Kim, Semin Cho, Hyeok Huh, Kwangsoo Kim in BMC Medicine (2022)

  4. Article

    Open Access

    Correction to: A multicentre, multi-national, double-blind, randomised, active-controlled, parallel-group clinical study to assess the safety and efficacy of PDA10 (Epoetin-Alfa) vs. Eprex® in patients with anaemia of chronic renal failure

    Soo Kun Lim, Bak Leong Goh, Ravindran Visvanathan, Su Hyun Kim in BMC Nephrology (2022)

  5. Article

    Open Access

    A multicentre, multi-national, double-blind, randomised, active-controlled, parallel-group clinical study to assess the safety and efficacy of PDA10 (Epoetin-Alfa) vs. Eprex® in patients with anaemia of chronic renal failure

    Erythropoietin stimulating agent (ESA) has been standard of care in treating renal anaemia for the past 20 years. Many patients have limited access to ESA in view of long-term costs leading to suboptimal ESA d...

    Soo Kun Lim, Bak Leong Goh, Ravindran Visvanathan, Su Hyun Kim in BMC Nephrology (2021)

  6. Article

    Open Access

    Causal effects of atrial fibrillation on brain white and gray matter volume: a Mendelian randomization study

    Atrial fibrillation (AF) and brain volume loss are prevalent in older individuals. We aimed to assess the causal effect of atrial fibrillation on brain volume phenotypes by Mendelian randomization (MR) analysis.

    Sehoon Park, Soo** Lee, Yaerim Kim, Semin Cho, Kwangsoo Kim, Yong Chul Kim in BMC Medicine (2021)

  7. Article

    Open Access

    Safety and efficacy of PG102P for the control of pruritus in patients undergoing hemodialysis (SNUG trial): study protocol for a randomized controlled trial

    Pruritus in patients undergoing hemodialysis is a highly prevalent complication that affects quality of life. Several medications are currently used for the treatment of uremic pruritus, but these are not sati...

    Yong Chul Kim, Jae Yoon Park, Sohee Oh, Jang-Hee Cho, Jae Hyun Chang in Trials (2019)

  8. Article

    Open Access

    The association of tumor necrosis factor superfamily 13 with recurrence of immunoglobulin A nephropathy in living related kidney transplantation

    An increasing amount of evidence has demonstrated an association between an increase in the level of tumor necrosis factor superfamily 13 (TNFSF13) and immunoglobulin A nephropathy (IgAN) progression. We aimed...

    Hyung Ah Jo, Seung Seok Han, Sunhwa Lee, Joo Young Kim, Seung Hee Yang in BMC Nephrology (2019)

  9. Article

    Open Access

    Factors affecting the long-term outcomes of idiopathic membranous nephropathy

    We attempted to describe the clinical features and determine the factors associated with renal survival in idiopathic membranous nephropathy (iMN) patients with nephrotic syndrome (NS) and to determine the fac...

    Hyuk Huh, Hajeong Lee, Jung Pyo Lee, Dong Ki Kim, Sohee Oh, Yun Kyu Oh in BMC Nephrology (2017)

  10. Article

    Open Access

    Early initiation of continuous renal replacement therapy improves survival of elderly patients with acute kidney injury: a multicenter prospective cohort study

    Continuous renal replacement therapy (CRRT) is essential in the management of critically ill patients with acute kidney injury (AKI). However, the optimal timing for initiating CRRT remains controversial, espe...

    Jae Yoon Park, Jung Nam An, Jong Hyun Jhee, Dong Ki Kim, Hyung Jung Oh in Critical Care (2016)

  11. Article

    Open Access

    Urinary adiponectin and albuminuria in non-diabetic hypertensive patients: an analysis of the ESPECIAL trial

    Although adiponectin levels have been reported to be correlated with albuminuria, this issue remains unresolved in non-diabetic hypertensive subjects, particularly when urinary adiponectin is considered.

    Seung Seok Han, Eun** Bae, Shin Young Ahn, Sejoong Kim, Jung Hwan Park in BMC Nephrology (2015)

  12. Article

    Open Access

    Pretransplant malnutrition, inflammation, and atherosclerosis affect cardiovascular outcomes after kidney transplantation

    Malnutrition, inflammation, and atherosclerosis (MIA) syndrome is associated with a high mortality rate in patients with end-stage renal disease. However, the clinical relevance of MIA syndrome in kidney trans...

    ** Ho Hwang, Jiwon Ryu, Jung Nam An, Clara Tammy Kim, Hyosang Kim in BMC Nephrology (2015)

  13. Article

    Open Access

    Non-linear association of serum 25-hydroxyvitamin D with urinary albumin excretion rate in normoalbuminuric subjects

    Vitamin D deficiencies and increases in urinary albumin excretion (UAE) are both important and potentially related health problems; however, the nature of their relationship has not been established in normoal...

    Yun Jung Oh, Rae Woong Park, Dukyong Yoon, Myounghee Kim, Seung Seok Han in BMC Nephrology (2014)

  14. Article

    Open Access

    Long-term prognosis of clinically early IgA nephropathy is not always favorable

    The long-term prognosis of clinically early IgA nephropathy (IgAN) patients remains to be clarified. We investigated the long-term outcomes of IgAN patients with an apparently benign presentation and evaluated...

    Hajeong Lee, ** Ho Hwang, ** Ho Paik, Hyun ** Ryu, Dong Ki Kim in BMC Nephrology (2014)

  15. Article

    Open Access

    Dose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug

    Dose selection is an important step in pharmacokinetic (PK) studies of hemodialysis patients. We propose a simulation-based dose-selection method for PK studies of hemodialysis patients using a subpharmacologi...

    Dong Ki Kim, Jay Wook Lee, Kwang-Hee Shin, Sejoong Kim, Kook-Hwan Oh in BMC Nephrology (2014)

  16. Article

    Open Access

    Effect of beraprost sodium on arterial stiffness in patients with type 2 diabetic nephropathy

    Diabetic nephropathy is the leading cause of end-stage renal disease (ESRD). Cardiovascular (CV) complications are the most common cause of death among ESRD patients. Beraprost sodium (BPS) is a prostacyclin a...

    Ki Young Na, Dong Ki Kim, Sung Gyun Kim, Young-Ki Lee, Chun Soo Lim in Trials (2013)

  17. Article

    Open Access

    Severe hyperkalemia requiring hospitalization: predictors of mortality

    Severe hyperkalemia, with potassium (K+) levels ≥ 6.5 mEq/L, is a potentially life-threatening electrolyte imbalance. For prompt and effective treatment, it is important to know its risk factors, clinical manifes...

    Jung Nam An, Jung Pyo Lee, Hee Jung Jeon, Do Hyoung Kim, Yun Kyu Oh in Critical Care (2012)

  18. Article

    Open Access

    The association of moderate renal dysfunction with impaired preference-based health-related quality of life: 3rdKorean national health and nutritional examination survey

    Only a few large-scale studies have investigated the association between health-related quality of life (HRQOL) and renal function. Moreover, the HRQOL of patients with moderate renal dysfunction is frequently...

    Hajeong Lee, Yun Jung Oh, Myounghee Kim, Ho Kim, Jung Pyo Lee in BMC Nephrology (2012)