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    Article

    N-acetylcysteine has neuroprotective effects against oxaliplatin-based adjuvant chemotherapy in colon cancer patients: preliminary data

    Although adding oxaliplatin to fluorouracil and leucovorin in adjuvant chemotherapy for colon cancer may improve disease-free survival, grade 3–4 sensory neuropathy also increases. To determine whether oral N-ace...

    Peng-Chan Lin, Ming-Yang Lee, Wei-Shu Wang, Chueh-Chuan Yen in Supportive Care in Cancer (2006)

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    Article

    Severe anaphylactic reactions in patients receiving oxaliplatin therapy: a rare but potentially fatal complication

    The most well-known adverse events of oxaliplatin are hematologic toxicity, gastrointestinal tract toxicity, and sensory neuropathy. However, hypersensitivity reaction of oxaliplatin, especially severe anaphyl...

    Ming-Yang Lee, Muh-Hwa Yang, **-Hwang Liu, Chueh-Chuan Yen in Supportive Care in Cancer (2007)

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    Article

    Duloxetine improves oxaliplatin-induced neuropathy in patients with colorectal cancer: an open-label pilot study

    This open-label pilot study is aimed to evaluate the efficacy and tolerability of the antidepressant duloxetine, which is effective for diabetic neuropathic pain, in the treatment of chronic oxaliplatin-induce...

    Ya-Hsu Yang, Jen-Kou Lin, Wei-Shone Chen, Tzu-Chen Lin in Supportive Care in Cancer (2012)