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    Open Access

    ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice

    Ribosome biogenesis plays a pivotal role in tumorigenesis by supporting robust protein translation. We investigate the functional and molecular mechanism of Zinc finger protein 545 (ZNF545), a transcriptional ...

    Shiyan Wang, Chi Chun Wong, Yanquan Zhang, Junzhe Huang, Chuangen Li in Oncogene (2021)