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Open AccessResearch progress on antitumor mechanisms and molecular targets of Inula sesquiterpene lactones
The pharmacological effects of natural product therapy have received sigificant attention, among which terpenoids such as sesquiterpene lactones stand out due to their biological activity and pharmacological p...
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Article
Assessing dynamic metabolic heterogeneity in non-small cell lung cancer patients via ultra-high sensitivity total-body [18F]FDG PET/CT imaging: quantitative analysis of [18F]FDG uptake in primary tumors and metastatic lymph nodes
This study aimed to quantitatively assess [18F]FDG uptake in primary tumor (PT) and metastatic lymph node (mLN) in newly diagnosed non-small cell lung cancer (NSCLC) using the total-body [18F]FDG PET/CT and to ch...
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Article
Open AccessHuman organoids in basic research and clinical applications
Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from healthy individuals or patients th...
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Article
Open AccessTLR2 deficiency promotes IgE and inhibits IgG1 class-switching following ovalbumin sensitization
To explore the roles of Toll-like receptor (TLR)2 in Th2 cytokine production and immunoglobulin (Ig) class switching following ovalbumin (OVA) sensitization.
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Article
Open AccessClinical warning of hemophagocytic syndrome caused by Epstein-Barr virus
This study aimed to compare the clinical features and laboratory tests of infectious mononucleosis (IM) and hemophagocytic syndrome (HLH) caused by Epstein-Barr virus (EBV) in 1–3-year-old children and to expl...
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Open AccessHigh expression of miR-222-3p in children with Mycoplasma pneumoniae pneumonia
Mycoplasma pneumoniae is a leading cause of community-acquired pneumonia in children. However, its mechanism of pathogenesis is not fully understood, and microRNAs might play a role. This study aimed to explor...
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Article
Open AccessThe relationship between air quality and respiratory pathogens among children in Suzhou City
We studied the short-term effects of air pollutant concentrations in Suzhou City on respiratory infections in children of different age groups.
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Open AccessHigh expression of HMGB1 in children with refractory Mycoplasma pneumoniae pneumonia
Increasing numbers of refractory or severe, even fatal, cases of Mycoplasma pneumoniae infections have been reported in recent years. Excessive inflammatory responses play a vital role in the pathogenesis of refr...