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  1. Article

    Open Access

    Research progress on antitumor mechanisms and molecular targets of Inula sesquiterpene lactones

    The pharmacological effects of natural product therapy have received sigificant attention, among which terpenoids such as sesquiterpene lactones stand out due to their biological activity and pharmacological p...

    Fei Cao, Chu Chu, Jiang-Jiang Qin, **aoqing Guan in Chinese Medicine (2023)

  2. No Access

    Article

    Assessing dynamic metabolic heterogeneity in non-small cell lung cancer patients via ultra-high sensitivity total-body [18F]FDG PET/CT imaging: quantitative analysis of [18F]FDG uptake in primary tumors and metastatic lymph nodes

    This study aimed to quantitatively assess [18F]FDG uptake in primary tumor (PT) and metastatic lymph node (mLN) in newly diagnosed non-small cell lung cancer (NSCLC) using the total-body [18F]FDG PET/CT and to ch...

    DaQuan Wang, Xu Zhang, Hui Liu, Bo Qiu in European Journal of Nuclear Medicine and M… (2022)

  3. Article

    Open Access

    Human organoids in basic research and clinical applications

    Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from healthy individuals or patients th...

    **ao-Yan Tang, Shanshan Wu, Da Wang, Chu Chu in Signal Transduction and Targeted Therapy (2022)

  4. Article

    Open Access

    TLR2 deficiency promotes IgE and inhibits IgG1 class-switching following ovalbumin sensitization

    To explore the roles of Toll-like receptor (TLR)2 in Th2 cytokine production and immunoglobulin (Ig) class switching following ovalbumin (OVA) sensitization.

    Yuqin Li, Qiu Chen, Wei Ji, Yujie Fan, Li Huang, Chu Chu in Italian Journal of Pediatrics (2021)

  5. Article

    Open Access

    Clinical warning of hemophagocytic syndrome caused by Epstein-Barr virus

    This study aimed to compare the clinical features and laboratory tests of infectious mononucleosis (IM) and hemophagocytic syndrome (HLH) caused by Epstein-Barr virus (EBV) in 1–3-year-old children and to expl...

    **** Shi, Chu Chu, Min Yu, Dandan Zhang, Yuqin Li in Italian Journal of Pediatrics (2021)

  6. Article

    Open Access

    High expression of miR-222-3p in children with Mycoplasma pneumoniae pneumonia

    Mycoplasma pneumoniae is a leading cause of community-acquired pneumonia in children. However, its mechanism of pathogenesis is not fully understood, and microRNAs might play a role. This study aimed to explor...

    Chu Chu, **aoli Lei, Yuqin Li, Yali Luo, Ying Ding in Italian Journal of Pediatrics (2019)

  7. Article

    Open Access

    The relationship between air quality and respiratory pathogens among children in Suzhou City

    We studied the short-term effects of air pollutant concentrations in Suzhou City on respiratory infections in children of different age groups.

    Dandan Zhang, Yuqin Li, Qiu Chen, Yanqun Jiang, Chu Chu in Italian Journal of Pediatrics (2019)

  8. Article

    Open Access

    High expression of HMGB1 in children with refractory Mycoplasma pneumoniae pneumonia

    Increasing numbers of refractory or severe, even fatal, cases of Mycoplasma pneumoniae infections have been reported in recent years. Excessive inflammatory responses play a vital role in the pathogenesis of refr...

    Ying Ding, Chu Chu, Yuqin Li, Gen Li, **aoli Lei, Weifang Zhou in BMC Infectious Diseases (2018)