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    Article

    Therapy of mRCC beyond mTOR-inhibition in clinical practice: results of a retrospective analysis

    Renal cell carcinoma (RCC) is the most common renal tumor and accounts for nearly 3 % of adult cancers. In the recent years, seven new targeted agents have been approved changing the treatment in metastatic R...

    Luise Maute, Viktor Grünwald in Journal of Cancer Research and Clinical On… (2014)

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    Article

    A retrospective review of diagnosis and treatment modalities of neuroendocrine tumors (excluding primary lung cancer) in 10 oncological institutions of the East German Study Group of Hematology and Oncology (OSHO), 2010–2012

    There is a paucity of data on the incidence of neuroendocrine tumors (NET) outside pulmonary primaries and on treatment modalities applied to patients with NET in clinical practice. Only very little therapeuti...

    Georg Maschmeyer, Lars-Olof Mügge in Journal of Cancer Research and Clinical On… (2015)

  3. No Access

    Article

    Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

    Hessell et al. report that post-exposure treatment with HIV-1–specific neutralizing antibodies clears SHIV infection from the blood and tissues of infant rhesus macaques.

    Ann J Hessell, J Pablo Jaworski, Erin Epson, Kenta Matsuda in Nature Medicine (2016)

  4. Article

    Open Access

    FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

    Cetuximab plus FOLFIRI improved overall survival compared with bevacizumab plus FOLFIRI in KRAS wild-type metastatic colorectal cancer (mCRC) in FIRE-3, but no corresponding benefit was found for progression-free...

    Volker Heinemann, Ludwig Fischer von Weikersthal in British Journal of Cancer (2021)

  5. Article

    Open Access

    Efficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3

    The evidence on the efficacy of anticancer therapy is limited in older patients with metastatic colorectal cancer (mCRC). This retrospective analysis of phase III FIRE-3 trial assesses the efficacy of FOLFIRI ...

    Laura E. Fischer, Sebastian Stintzing in British Journal of Cancer (2022)