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    Article

    Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

    Hessell et al. report that post-exposure treatment with HIV-1–specific neutralizing antibodies clears SHIV infection from the blood and tissues of infant rhesus macaques.

    Ann J Hessell, J Pablo Jaworski, Erin Epson, Kenta Matsuda in Nature Medicine (2016)

  2. Article

    Open Access

    FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

    Cetuximab plus FOLFIRI improved overall survival compared with bevacizumab plus FOLFIRI in KRAS wild-type metastatic colorectal cancer (mCRC) in FIRE-3, but no corresponding benefit was found for progression-free...

    Volker Heinemann, Ludwig Fischer von Weikersthal in British Journal of Cancer (2021)

  3. Article

    Open Access

    Efficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3

    The evidence on the efficacy of anticancer therapy is limited in older patients with metastatic colorectal cancer (mCRC). This retrospective analysis of phase III FIRE-3 trial assesses the efficacy of FOLFIRI ...

    Laura E. Fischer, Sebastian Stintzing in British Journal of Cancer (2022)