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    Article

    Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures

    Quinolone-induced arthropathy is probably caused by a lack of functionally available magnesium in immature joint cartilage. We used an in vitro assay to study the effects of fluoroquinolones on cartilage form...

    Christian Förster, Marcus Rücker, Mehdi Shakibaei… in Archives of Toxicology (1998)

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    Article

    In vitro evidence for a Donnan distribution of Mg 2+ and Ca2+ by chondroitin sulphate in cartilage

    Fluoroquinolones are known for their ability to form chelate complexes with magnesium. Cartilage lesions observed in juvenile animals after quinolone treatment very probably are a consequence of the lack of f...

    Theodor Günther, Marcus Rücker, Christian Förster, Jürgen Vormann… in Archives of Toxicology (1997)