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Chris Kedong Wang
English
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Article
Open AccessReformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer
Lineage plasticity of prostate cancer is associated with resistance to androgen receptor (AR) pathway inhibition (ARPI) and supported by a reactive tumor microenvironment. Here we show that changes in chondroi...
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Article
Open AccessInternalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells
Proteoglycans are proteins that are modified with glycosaminoglycan chains. Chondroitin sulfate proteoglycans (CSPGs) are currently being exploited as targets for drug-delivery in various cancer indications, h...
