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Chromatin reprogramming and bone regeneration in vitro and in vivo via the microtopography-induced constriction of cell nuclei

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  1. Article

    Open Access

    The susceptibility of cochlear outer hair cells to cyclodextrin is not related to their electromotile activity

    Niemann-Pick Type C1 (NPC1) disease is a fatal neurovisceral disorder caused by dysfunction of NPC1 protein, which plays a role in intracellular cholesterol trafficking. The cholesterol-chelating agent, 2-hydr...

    Yingjie Zhou, Satoe Takahashi, Kazuaki Homma… in Acta Neuropathologica Communications (2018)

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  2. Article

    Open Access

    Susceptibility of outer hair cells to cholesterol chelator 2-hydroxypropyl-β-cyclodextrine is prestin-dependent

    Niemann-Pick type C1 disease (NPC1) is a fatal genetic disorder caused by impaired intracellular cholesterol trafficking. Recent studies reported ototoxicity of 2-hydroxypropyl- β-cyclodextrin (HPβCD), a chole...

    Satoe Takahashi, Kazuaki Homma, Yingjie Zhou, Shinichi Nishimura… in Scientific Reports (2016)

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