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  1. Article

    Open Access

    A deep learning-based algorithm for pulmonary tuberculosis detection in chest radiography

    In tuberculosis (TB), chest radiography (CXR) patterns are highly variable, mimicking pneumonia and many other diseases. This study aims to evaluate the efficacy of Google teachable machine, a deep neural netw...

    Chiu-Fan Chen, Chun-Hsiang Hsu, You-Cheng Jiang, Wen-Ren Lin in Scientific Reports (2024)

  2. Article

    Open Access

    Burnout during the COVID-19 pandemic among nurses in Taiwan: the parental role effect on burnout

    During the COVID-19 pandemic, medical workers were concerned about the care of their children or family members and the impact of being separated from them. This increased stress could harm the relationship be...

    Yong-Hsin Chen, Mohsen Saffari, Chung-Ying Lin in BMC Health Services Research (2024)

  3. No Access

    Article

    Research trends in alopecia areata: a cross-sectional bibliometric analysis of the top cited studies

    In the field of alopecia areata research, various focuses including risk factors, epidemiology, molecular pathways, and treatment were constantly improving. However, to date, a bibliometric analysis summarizin...

    Hui-Chin Chang, Tsu-Man Chiu, Chien-Ying Lee in Archives of Dermatological Research (2024)

  4. No Access

    Article

    Facilitating Mathematical Argumentation by Gamification: A Gamified Mobile Collaborative Learning Approach for Math Courses

    Collaborative mathematical argumentation plays an important role in mathematics education. However, students often focus on the efficiency of solving problems and neglect the importance of expressing statement...

    Wei-Cheng Lee, Chiu-Lin Lai in International Journal of Science and Mathematics Education (2024)

  5. Article

    Open Access

    Poor personal protective equipment practices were associated with heat-related symptoms among Asian healthcare workers: a large-scale multi-national questionnaire survey

    It is pertinent to understand the perceptions of healthcare workers (HCWs) with their associated personal protective equipment (PPE) usage and heat strain symptoms experienced to effectively combat the negativ...

    Hsiao-Yu Yang, Hsiu-Ling Chou, Clarence Hong Wei Leow, Ching-Chiu Kao in BMC Nursing (2024)

  6. Article

    Open Access

    Upregulated microRNA-125b-5p in patients with asthma-COPD overlap mediates oxidative stress and late apoptosis via targeting IL6R/TRIAP1 signaling

    Among patients with chronic obstructive pulmonary disease (COPD), some have features of both asthma and COPD—a condition categorized as asthma-COPD overlap (ACO). Our aim was to determine whether asthma- or CO...

    Yu-** Chang, Yi-Hsuan Tsai, Yu-Mu Chen, Kuo-Tung Huang in Respiratory Research (2024)

  7. No Access

    Article

    Long non-coding RNA FKSG29 regulates oxidative stress and endothelial dysfunction in obstructive sleep apnea

    Altered expressions of pro-/anti-oxidant genes are known to regulate the pathophysiology of obstructive sleep apnea (OSA).We aim to explore the role of a novel long non-coding (lnc) RNA FKSG29 in the developme...

    Yung-Che Chen, Po-Yuan Hsu, Mao-Chang Su in Molecular and Cellular Biochemistry (2023)

  8. No Access

    Article

    Quality of life and cost-effectiveness of different breast cancer surgery procedures: a Markov decision tree-based approach in the framework of Predictive, Preventive, and Personalized Medicine

    Breast cancer is a complex disease with heterogeneous outcomes that may benefit from the implementation of Predictive, Preventive, and Personalized Medicine (PPPM/3PM) strategies. In this study, we aimed to ex...

    Hon-Yi Shi, Chiu-Hui Li, Yen-Chen Chen, Chong-Chi Chiu, Hao-Hsien Lee in EPMA Journal (2023)

  9. Article

    Open Access

    Psychometric properties of the Chinese Mandarin version of the Borderline Symptom List, short form (BSL-23) in suicidal adolescents

    The short form of the Borderline Symptom List (BSL-23) is a self-rated instrument developed from the initial 95-item German version of the Borderline Symptom List (BSL-95). It is widely used among Chinese adul...

    Jui-En Shen, Yu-Hsin Huang, Hui-Chun Huang in Borderline Personality Disorder and Emotio… (2023)

  10. No Access

    Article

    Determination of potential sources of heavy metals in patients with urothelial carcinoma in central Taiwan: a biomonitoring case–control study

    The clarification of possible exposure sources of multiple metals to identify associations between metal doses and urothelial carcinoma (UC) risk is currently limited in the literature. We sought to identify t...

    Chi-Jung Chung, Hui-Ling Lee, Chao-Hsiang Chang in Environmental Geochemistry and Health (2023)

  11. Article

    Open Access

    Trends in energy and macronutrient intake among Taiwanese older adults in 1999–2000, 2005–2008 and 2013–2016 periods

    This study aimed to explore trends, in 3 periods, in the intake of energy and macronutrients among Taiwanese older adults.

    Chih-Hsueh Lin, Hsing-Yi Chang, Tsai-Chung Li, Chiu-Shong Liu in BMC Public Health (2023)

  12. Article

    Open Access

    Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma

    Neutrophils are dynamic with their phenotype and function shaped by the microenvironment, such as the N1 antitumor and N2 pro-tumor states within the tumor microenvironment (TME), but its regulation remains un...

    Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Max Kam-Kwan Chan in Nature Communications (2023)

  13. Article

    Open Access

    Early detection of myocardial ischemia in resting ECG: analysis by HHT

    Exercise electrocardiography (ECG) is a noninvasive test aiming at producing ischemic changes. However, resting ECG cannot be adopted in diagnosing myocardial ischemia till ST-segment depressions. Therefore, t...

    Chun-Lin Wang, Chiu-Chi Wei, Cheng-Ting Tsai in BioMedical Engineering OnLine (2023)

  14. Article

    Open Access

    Autophagy impairment in patients with obstructive sleep apnea modulates intermittent hypoxia-induced oxidative stress and cell apoptosis via hypermethylation of the ATG5 gene promoter region

    Autophagy is a catabolic process that recycles damaged organelles and acts as a pro-survival mechanism, but little is known about autophagy dysfunction and epigenetic regulation in patients with obstructive sl...

    Yung-Che Chen, I-Chun Lin, Mao-Chang Su in European Journal of Medical Research (2023)

  15. No Access

    Chapter

    Malignant Neoplasms of the Small Intestines

    Malignant neoplasms are very rare disease regardless of primary or secondary. The diagnosis of small intestine malignant tumor is challenging. In this chapter, the authors presented various malignant diseases ...

    Ming-Luen Hu, Yi-Chun Chiu, Wei-Chen Tai in Atlas of Small Intestinal Disorders (2023)

  16. No Access

    Chapter

    Benign Neoplasms of the Small Intestines

    Benign neoplasms of the small intestine are covered in this chapter. Small intestine tumors accounted for 5% of all gastrointestinal tract tumors. Approximately 60% of these tumors were benign. All these cases...

    Jen-Wei Chou, Shang-Fen Huang, Chung-Wei Chen in Atlas of Small Intestinal Disorders (2023)

  17. No Access

    Chapter

    Miscellaneous Disorder of the Small Intestines

    In this chapter, miscellaneous disorder/diseases were presented. In this chapter, a variety of small bowel disorders/diseases of the small bowel was presented with clinical history, pictures of enteroscopy or ...

    Chen-Shuan Chung, Tzong-His Lee, Jen-Wei Chou in Atlas of Small Intestinal Disorders (2023)

  18. No Access

    Chapter

    Vascular Disorders of the Small Intestines

    Vascular lesions constituted a major proportion (21% to 57%) of all small intestinal obscure gastrointestinal bleeding cases. It is one important cause of obscure gastrointestinal bleeding and diagnosis is cha...

    Wen-Hung Hsu, Fang-Jung Yu, Deng-Chyang Wu in Atlas of Small Intestinal Disorders (2023)

  19. Article

    Open Access

    Fifty-year change in air pollution in Kaohsiung, Taiwan

    The change in air quality in cities can be the product of regulation and emissions. Regulations require enforcement of emission reduction, but it is often shifting economic and societal structures that influen...

    Chiu-Hsuan Lee, Peter Brimblecombe in Environmental Science and Pollution Resear… (2022)

  20. Article

    Open Access

    Sequentially mediated effects of weight-related self-stigma and psychological distress in the association between perceived weight stigma and food addiction among Taiwanese university students: A cross-sectional study

    Weight-related stigma has negative physiological and psychological impacts on individuals’ quality of life. Stigmatized individuals may experience higher psychological distress and therefore increase the poten...

    Po-Ching Huang, Chiu-Hsiang Lee, Mark D. Griffiths in Journal of Eating Disorders (2022)

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