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Article
Open AccessLongitudinal multicompartment characterization of host-microbiota interactions in patients with acute respiratory failure
Critical illness can significantly alter the composition and function of the human microbiome, but few studies have examined these changes over time. Here, we conduct a comprehensive analysis of the oral, lung...
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Article
Open AccessMetagenomic assessment of gut microbial communities and risk of severe COVID-19
The gut microbiome is a critical modulator of host immunity and is linked to the immune response to respiratory viral infections. However, few studies have gone beyond describing broad compositional alteration...
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Article
Open AccessGlutamine induces remodeling of tight junctions in Caco-2 colorectal cancer cell
Malignant cells often exhibit significant metabolic alterations, including the utilization of different nutrients to meet energetic and biosynthetic demands. Recent studies have shown that glutamine can suppor...
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Article
Open AccessEffects of positive end-expiratory pressure on the predictability of fluid responsiveness in acute respiratory distress syndrome patients
The prediction accuracy of pulse pressure variation (PPV) for fluid responsiveness was suggested to be unreliable in low tidal volume (VT) ventilation. However, high PEEP can cause ARDS patients relatively hyp...
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Article
Open AccessCopy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank
The Taiwan Human Disease iPSC Service Consortium was established to accelerate Taiwan’s growing stem cell research initiatives and provide a platform for researchers interested in utilizing induced pluripotent...
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Article
Open AccessHuman iPSC banking: barriers and opportunities
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new opportunities for regenerative medicine, disease modeling, iPSC-based d...
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Article
How background, motivation, and the cooperation tie of faculty members affect their university–industry collaboration outputs: an empirical study based on Taiwan higher education environment
University–industry collaboration (UIC) has been booming for several decades worldwide. Integrating knowledge and resources from universities and industries has become a common method to maintain the innovatio...
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Article
Tumor Necrosis Factor α-Dependent Neutrophil Priming Prevents Intestinal Ischemia/Reperfusion-Induced Bacterial Translocation
Intestinal ischemia/reperfusion (I/R) causes barrier impairment and bacterial influx. Protection against I/R injury in sterile organs by hypoxic preconditioning (HPC) had been attributed to erythropoietic and ...
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Article
Effect of Co substitution for Mn on Y1−x Sr x MnO3 properties for SOFC cathode material
Y0.6Sr0.4Mn1−y Co y O3 (0 ≤ y ≤ 0.4) perovskite oxides were prepared by the coprecipitation method. The effect of Co substitution for Mn on the crystal structure, electrical cond...
