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  1. Article

    Open Access

    Real-World Treatment Patterns After CD19-Directed CAR T Cell Therapy Among Patients with Diffuse Large B Cell Lymphoma

    CD19-directed chimeric antigen receptor T cells (CAR T) are approved for treatment of adults with relapsed/refractory diffuse large B cell lymphoma (DLBCL) following at least two lines of therapy.

    Jessica J. Jalbert, Ning Wu, Chieh-I Chen, Srikanth Ambati in Advances in Therapy (2022)

  2. Article

    Open Access

    Economic Evaluation of Sarilumab in the Treatment of Adult Patients with Moderately-to-Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs

    Assess the cost-effectiveness (US healthcare payer perspective) of sarilumab subcutaneous (SC) 200 mg + methotrexate versus conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) or targeted ...

    Noemi Muszbek, Clare Proudfoot, Marie Fournier, Chieh-I Chen in Advances in Therapy (2019)

  3. Article

    Open Access

    Indirect Treatment Comparison of the Efficacy and Safety of Sarilumab Monotherapy in Rheumatoid Arthritis Patients with Inadequate Response to Conventional Disease-Modifying Antirheumatic Drugs

    To evaluate the comparative efficacy and safety of subcutaneous sarilumab 200 mg monotherapy administered every 2 weeks (q2w) versus other monotherapies of biologic, targeted and conventional synthetic disease...

    Ernest Choy, Nick Freemantle, Clare Proudfoot, Chieh-I Chen in Advances in Therapy (2019)

  4. Article

    Open Access

    Treatment Persistence and Healthcare Costs Among Patients with Rheumatoid Arthritis Changing Biologics in the USA

    After a patient with rheumatoid arthritis (RA) fails tumor necrosis factor inhibitor (TNFi) treatment, clinical guidelines support either cycling to another TNFi or switching to a different mechanism of action...

    Benjamin Chastek, Chieh-I Chen, Clare Proudfoot, Shraddha Shinde in Advances in Therapy (2017)

  5. Article

    Open Access

    Treatment Persistence and Clinical Outcomes of Tumor Necrosis Factor Inhibitor Cycling or Switching to a New Mechanism of Action Therapy: Real-world Observational Study of Rheumatoid Arthritis Patients in the United States with Prior Tumor Necrosis Factor Inhibitor Therapy

    To examine treatment persistence and clinical outcomes associated with switching from a tumor necrosis factor inhibitor (TNFi) to a medication with a new mechanism of action (MOA) (abatacept, anakinra, rituxim...

    Wenhui Wei, Keith Knapp, Li Wang, Chieh-I Chen, Gary L. Craig in Advances in Therapy (2017)