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Article
Open AccessAmyloid-β accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism
Astrocytes play a central role in maintaining brain energy metabolism, but are also tightly connected to the pathogenesis of Alzheimer’s disease (AD). Our previous studies demonstrate that inflammatory astrocy...
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Article
Open AccessIntracellular deposits of amyloid-beta influence the ability of human iPSC-derived astrocytes to support neuronal function
Astrocytes are crucial for maintaining brain homeostasis and synaptic function, but are also tightly connected to the pathogenesis of Alzheimer’s disease (AD). Our previous data demonstrate that astrocytes ing...