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  1. Article

    Open Access

    Amyloid-β accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

    Astrocytes play a central role in maintaining brain energy metabolism, but are also tightly connected to the pathogenesis of Alzheimer’s disease (AD). Our previous studies demonstrate that inflammatory astrocy...

    Marlena Zyśk, Chiara Beretta, Luana Naia in Journal of Neuroinflammation (2023)

  2. Article

    Open Access

    Intracellular deposits of amyloid-beta influence the ability of human iPSC-derived astrocytes to support neuronal function

    Astrocytes are crucial for maintaining brain homeostasis and synaptic function, but are also tightly connected to the pathogenesis of Alzheimer’s disease (AD). Our previous data demonstrate that astrocytes ing...

    Evangelos Konstantinidis, Benjamin Portal, Tobias Mothes in Journal of Neuroinflammation (2023)