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  1. Article

    Open Access

    BAFF-driven NLRP3 inflammasome activation in B cells

    BAFF supports B-cell survival and homeostasis by activating the NF-κB pathway. While NF-κB is also involved in the priming signal of NLRP3 inflammasome, the role of BAFF in NLRP3 inflammasome regulation is unk...

    Ken-Hong Lim, Lih-Chyang Chen, Kate Hsu, Chia-Ching Chang in Cell Death & Disease (2020)

  2. No Access

    Chapter

    Design of Nanodiamond Based Drug Delivery Patch for Cancer Therapeutics and Imaging Applications

    The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can ...

    Wing Kam Liu, Ashfaq Adnan, Adrian M. Kopacz, Michelle Hallikainen, Dean Ho in Nanodiamonds (2010)

  3. No Access

    Article

    Direct Observation of Single Molecule Conformational Change of Tight-Turn Paperclip DNA Triplex in Solution

    DNA triplex modulates gene expression by forming stable conformation in physiological condition. However, it is not feasible to observe this unique molecular structure of large molecule with 54 oligodeoxynucle...

    Ching-** Liu, Ming-Tsai Wey, Chia-Ching Chang in Applied Biochemistry and Biotechnology (2009)