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  1. No Access

    Article

    Examining the role of living alone and loneliness in predicting health-related quality of life: results from the Healthy Aging Longitudinal Study in Taiwan (HALST)

    This study aimed to investigate the distinct yet interconnected aspects of social isolation, namely living alone and loneliness, and their individual and combined effects on predicting health-related quality o...

    Han-Yun Tseng, Chun-Yi Lee, Chi-Shin Wu, I.-Chien Wu in Quality of Life Research (2024)

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    Article

    Paternal age and 13 psychiatric disorders in the offspring: a population-based cohort study of 7 million children in Taiwan

    Although paternal age has been linked to certain psychiatric disorders, the nature of any causal relationship remains elusive. Here, we aimed to comprehensively assess the magnitude of a wide range of offsprin...

    Shi-Heng Wang, Chi-Shin Wu, Le-Yin Hsu, Mei-Chen Lin, Pei-Chun Chen in Molecular Psychiatry (2022)

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    Article

    Causality of abdominal obesity on cognition: a trans-ethnic Mendelian randomization study

    Obesity has been associated with cognition in observational studies; however, whether its effect is confounding or a reverse causality remains inconclusive. This study aimed to investigate the causal relations...

    Shi-Heng Wang, Mei-Hsin Su, Chia-Yen Chen, Yen-Feng Lin in International Journal of Obesity (2022)

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    Article

    Neurodevelopmental model of schizophrenia revisited: similarity in individual deviation and idiosyncrasy from the normative model of whole-brain white matter tracts and shared brain-cognition covariation with ADHD and ASD

    The neurodevelopmental model of schizophrenia is supported by multi-level impairments shared among schizophrenia and neurodevelopmental disorders. Despite schizophrenia and typical neurodevelopmental disorders...

    Yi-Ling Chien, Hsiang-Yuan Lin, Yu-Hung Tung, Tzung-Jeng Hwang in Molecular Psychiatry (2022)

  5. Article

    Open Access

    Determinants of effective treatment coverage for major depressive disorder in the WHO World Mental Health Surveys

    Most individuals with major depressive disorder (MDD) receive either no care or inadequate care. The aims of this study is to investigate potential determinants of effective treatment coverage.

    Daniel V. Vigo, Alan E. Kazdin in International Journal of Mental Health Sys… (2022)

  6. Article

    Familial aggregation and shared genetic loading for major psychiatric disorders and type 2 diabetes

    Psychiatric disorders, such as schizophrenia (SCZ), major depressive disorder (MDD) and bipolar disorder (BPD), are highly comorbid with type 2 diabetes. However, the mechanisms underlying such comorbidity are...

    Mei-Hsin Su, Ying-Hsiu Shih, Yen-Feng Lin, Pei-Chun Chen, Chia-Yen Chen in Diabetologia (2022)