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    Article

    Aldosteronism is associated with more severe cerebral small vessel disease in hypertensive intracerebral hemorrhage

    Primary aldosteronism is associated with various types of cardiovascular and cerebrovascular damage independently of hypertension. Although chronic hypertension and related cerebral arteriosclerosis are the ma...

    Bo-Ching Lee, Hsin-Hsi Tsai, Zheng-Wei Chen, Chin-Chen Chang in Hypertension Research (2024)

  2. Article

    Open Access

    Heart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction

    Heart rhythm complexity (HRC), a subtype of heart rate variability (HRV), is an important tool to investigate cardiovascular disease. In this study, we aimed to analyze serial changes in HRV and HRC metrics in...

    Shu-Yu Tang, Hsi-Pin Ma, Chen Lin, Men-Tzung Lo, Lian-Yu Lin in Scientific Reports (2023)

  3. Article

    Agreement regarding overcoming hypertension in the Asian Hypertension Society Network 2022

    Satoshi Hoshide, Koichi Yamamoto, Kenichi Katsurada, Yuichiro Yano in Hypertension Research (2023)

  4. Article

    Open Access

    Comparison between drug-coated balloons and drug-eluting stents in very small coronary artery interventions

    The optimal management of very small vessel (reference diameter from 2.0 to 2.25 mm) in percutaneous coronary interventions (PCIs) is controversial. We aimed to compare the efficacy and safety of drug-coated b...

    Cheng-Hsuan Tsai, Chih-Fan Yeh, Shih-Wei Meng, Chi-Sheng Hung in Scientific Reports (2022)

  5. Article

    The efficacy and safety of novel classes of glucose-lowering drugs for cardiovascular outcomes: a network meta-analysis of randomised clinical trials

    Several cardiovascular outcome trials on sodium–glucose cotransporter 2 inhibitors (SGLT2i) have been released recently, including trials enrolling patients with congestive heart failure (CHF) and chronic kidn...

    Donna Shu-Han Lin, Jen-Kuang Lee, Chi-Sheng Hung, Wen-Jone Chen in Diabetologia (2021)

  6. Article

    Open Access

    The periprocedural and 30-day outcomes of carotid stenting in patients with carotid artery near-occlusion

    The safety of endovascular revascularization in patients with carotid artery near occlusion (CANO) is unknown. We aimed to evaluate the peri-procedural risk in CANO patients receiving carotid artery stenting (...

    Cheng-Hsuan Tsai, Ying-Hsien Chen, Mao-Shin Lin, Ching-Chang Huang in Scientific Reports (2021)

  7. Article

    Open Access

    Impact of conduction disturbances on left ventricular mass regression and geometry change following transcatheter aortic valve replacement

    Our study aimed to compare the difference of LV mass regression and remodeling in regard of conduction disturbances (CD) following transcatheter aortic valve replacement (TAVR). A prospective analysis of 152 c...

    Tsung-Yu Ko, Hsien-Li Kao, Ying-Ju Liu, Chih-Fan Yeh in Scientific Reports (2021)

  8. Article

    Open Access

    Left ventricular remodeling and dysfunction in primary aldosteronism

    Primary aldosteronism (PA) is a common cause of secondary hypertension and is associated with worse cardiovascular outcomes. The elevated aldosterone in PA leads to left ventricular (LV) remodeling and dysfunc...

    Cheng-Hsuan Tsai, Chien-Ting Pan, Yi-Yao Chang in Journal of Human Hypertension (2021)

  9. Article

    Open Access

    Usefulness of heart rhythm complexity in heart failure detection and diagnosis

    Heart failure (HF) is a major cardiovascular disease worldwide, and the early detection and diagnosis remain challenges. Recently, heart rhythm complexity analysis, derived from non-linear heart rate variabili...

    Cheng-Hsuan Tsai, Hsi-Pin Ma, Yen-Tin Lin, Chi-Sheng Hung in Scientific Reports (2020)

  10. Article

    Open Access

    Heart Rhythm Complexity Impairment in Patients with Pulmonary Hypertension

    Pulmonary hypertension is a fatal disease, however reliable prognostic tools are lacking. Heart rhythm complexity analysis is derived from non-linear heart rate variability (HRV) analysis and has shown excelle...

    Cheng-Hsuan Tsai, Hsi-Pin Ma, Yen-Tin Lin, Chi-Sheng Hung in Scientific Reports (2019)

  11. Article

    Open Access

    Chronic wound assessment and infection detection method

    Numerous patients suffer from chronic wounds and wound infections nowadays. Until now, the care for wounds after surgery still remain a tedious and challenging work for the medical personnel and patients. As ...

    Jui-Tse Hsu, Yung-Wei Chen, Te-Wei Ho in BMC Medical Informatics and Decision Making (2019)

  12. Article

    Open Access

    Inhibition of Semicarbazide-sensitive Amine Oxidase Reduces Atherosclerosis in Cholesterol-fed New Zealand White Rabbits

    Inflammation, oxidative stress, and the formation of advanced glycated end-products (AGEs) are important components of atherosclerosis. Vascular adhesion protein-1 (VAP-1) participates in inflammation. Its enz...

    Shu-Huei Wang, Tse-Ya Yu, Chi-Sheng Hung, Chung-Yi Yang, Mao-Shin Lin in Scientific Reports (2018)

  13. Article

    Open Access

    Prevalence and outcome of patients with non-ST segment elevation myocardial infarction with occluded “culprit” artery – a systemic review and meta-analysis

    The aim was to determine the prevalence and impact of an occluded “culprit” artery (OCA) in patients with non-ST segment elevation myocardial infarction (NSTEMI).

    Chi-Sheng Hung, Ying-Hsien Chen, Ching-Chang Huang, Mao-Shin Lin in Critical Care (2018)

  14. Article

    Open Access

    Identification of Atrial Fibrillation by Quantitative Analyses of Fingertip Photoplethysmogram

    Atrial fibrillation (AF) detection is crucial for stroke prevention. We investigated the potential of quantitative analyses of photoplethysmogram (PPG) waveforms to identify AF. Continuous electrocardiogram (E...

    Sung-Chun Tang, Pei-Wen Huang, Chi-Sheng Hung, Shih-Ming Shan in Scientific Reports (2017)

  15. Article

    Open Access

    Serial heart rhythm complexity changes in patients with anterior wall ST segment elevation myocardial infarction

    Heart rhythm complexity analysis has been shown to have good prognostic power in patients with cardiovascular disease. The aim of this study was to analyze serial changes in heart rhythm complexity from the ac...

    Hung-Chih Chiu, Hsi-Pin Ma, Chen Lin, Men-Tzung Lo, Lian-Yu Lin in Scientific Reports (2017)

  16. Article

    Open Access

    Time course and factors predicting arterial stiffness reversal in patients with aldosterone-producing adenoma after adrenalectomy: prospective study of 102 patients

    Primary aldosteronism not only results in hypertension but also stiffer arteries. The time course and factors predicting the reversal of arterial stiffness after treatment are unclear. We prospectively enrolle...

    Che-Wei Liao, Lian-Yu Lin, Chi-Sheng Hung, Yen-Tin Lin, Yi-Yao Chang in Scientific Reports (2016)

  17. Article

    Open Access

    Reversible heart rhythm complexity impairment in patients with primary aldosteronism

    Excess aldosterone secretion in patients with primary aldosteronism (PA) impairs their cardiovascular system. Heart rhythm complexity analysis, derived from heart rate variability (HRV), is a powerful tool to ...

    Yen-Hung Lin, Vin-Cent Wu, Men-Tzung Lo, Xue-Ming Wu, Chi-Sheng Hung in Scientific Reports (2015)