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    Article

    Histone H4 deacetylation down-regulates catalase gene expression in doxorubicin-resistant AML subline

    We explored if epigenetic mechanisms could be involved in the down-regulated expression of catalase gene (CAT) in the doxorubicin-resistant acute myelogenous leukemia (AML)-2/DX100 cells. Down-regulated CAT expre...

    Tae-Bum Lee, Young-Sook Moon, Cheol-Hee Choi in Cell Biology and Toxicology (2012)

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    Article

    Reactive Oxygen Species-specific Mechanisms of Drug Resistance in Paraquat-resistant Acute Myelogenous Leukemia Sublines

    Reactive oxygen species (ROS)-specific mechanisms of drug resistance were explored in paraquat (PQ)-resistant acute myelogenous leukemia cell (OCI/AML-2) sublines. For this, PQ-resistant AML sublines, AML-2/PQ...

    Cheol-Hee Choi, Hyang-Sook Kim, Oh-Seong Kweon, Tae-Bum Lee… in Molecules and Cells (2000)