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Article
Open AccessReal-world practice of conversion surgery for unresectable hepatocellular carcinoma - a single center data of 26 consecutive patients
To understand the proportion of uHCC (unresectable hepatocellular carcinoma) patients who achieve successful conversion resection in a high-volume setting with state of the art treatment options.
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Article
Open AccessA novel treatment strategy for lapatinib resistance in a subset of HER2-amplified gastric cancer
Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Human epidermal growth factor receptor 2 (HER2) amplification occurs in approximately 13–23% of all GC cases and patients wi...
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Article
Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences
Chris Tyler-Smith, Carlos Bustamante and colleagues report an analysis of 1,244 human Y chromosomes from the 1000 Genomes Project. They find that copy number variants have a higher predicted functional impact ...