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  1. Article

    Open Access

    N-acetylcysteine as add-on to antidepressant medication in therapy refractory major depressive disorder patients with increased inflammatory activity: study protocol of a double-blind randomized placebo-controlled trial

    A subgroup of depressed patients with increased inflammatory activity was shown to be more susceptible to develop Treatment Resistant Depression (TRD). Earlier studies with anti-inflammatory drugs have shown b...

    Chenghao Yang, Fokko J. Bosker, Jie Li, Robert A. Schoevers in BMC Psychiatry (2018)

  2. No Access

    Article

    Chronic exposure to fluoxetine of female mice before mating causes impaired stress resilience in female offspring

    Antidepressant agents have been proven their utilities in treating depression, but they also could serve as candidate drugs for misuse or abuse due to diverse pharmacologic properties. Potential detriments had...

    Chenghao Yang, Jijian Si, Lin Suo, Yan Zhang, Jie Li in Journal of Neural Transmission (2019)

  3. No Access

    Article

    Autophagy markers, cognitive deficits and depressive symptoms in Parkinson’s disease

    Depressive symptoms are common in Parkinson’s disease (PD). The relationships between autophagy and PD or depression have been documented. However, no studies explored the role of autophagy markers associated ...

    Yanzhe Li, Hechao Yang, Peng Zhao, Junfeng Yang, Cong Yao in Journal of Neural Transmission (2024)