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    Open Access

    N-acetylcysteine as add-on to antidepressant medication in therapy refractory major depressive disorder patients with increased inflammatory activity: study protocol of a double-blind randomized placebo-controlled trial

    A subgroup of depressed patients with increased inflammatory activity was shown to be more susceptible to develop Treatment Resistant Depression (TRD). Earlier studies with anti-inflammatory drugs have shown b...

    Chenghao Yang, Fokko J. Bosker, Jie Li, Robert A. Schoevers in BMC Psychiatry (2018)