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Selinexor demonstrates anti-tumor efficacy in paired patient-derived xenograft models and hydrogel-embedded histoculture drug sensitivity test of penile cancer

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  1. Article

    Publisher Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Huilin Huang, Hengyou Weng, Wenju Sun, ** Qin, Hailing Shi… in Nature Cell Biology (2020)

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  2. Article

    Open Access

    Body mass index-associated molecular characteristics involved in tumor immune and metabolic pathways

    Overweight or obesity has been evidenced as an important risk factor involved in the incidence, mortality, and therapy response of multiple malignancies. However, the differences between healthy and obesity tu...

    Chao Hu, **ong Chen, Chengyun Yao, Yu Liu, Haojun Xu, Guoren Zhou… in Cancer & Metabolism (2020)

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  3. Article

    Open Access

    Higher matrix stiffness as an independent initiator triggers epithelial-mesenchymal transition and facilitates HCC metastasis

    Increased liver stiffness exerts a detrimental role in driving hepatocellular carcinoma (HCC) malignancy and progression, and indicates a high risk of unfavorable outcomes. However, it remains largely unknown ...

    Yinying Dong, Qiongdan Zheng, Zhiming Wang, **ahui Lin… in Journal of Hematology & Oncology (2019)

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  4. Article

    Open Access

    NRAS and KRAS polymorphisms are not associated with hepatoblastoma susceptibility in Chinese children

    Hepatoblastoma is the most common hepatic malignancy in children, accounting for approximately 80% of all childhood liver tumors. KRAS and NRAS, members of the RAS gene family, are closely linked to tumorigenesis...

    Tianyou Yang, Yang Wen, Jiahao Li, Tianbao Tan… in Experimental Hematology & Oncology (2019)

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  5. Article

    Open Access

    A critical role of epigenetic inactivation of miR-9 in EVI1high pediatric AML

    Ectopic Viral Integration site 1 (EVI1) upregulation is implicated in 10–25% of pediatric acute myeloid leukemia (AML) and has an inferior outcome with current chemotherapy regimens. Here we report that EVI1 u...

    Nupur Mittal, Li** Li, Yue Sheng, Chao Hu, Fuxing Li, Tongyu Zhu… in Molecular Cancer (2019)

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  6. Article

    Open Access

    The rs2147578 C > G polymorphism in the Inc-LAMC2–1:1 gene is associated with increased neuroblastoma risk in the Henan children

    The rs2147578 C > G polymorphism in the long non-coding RNA gene Lnc-LAMC2–1:1 is associated with increased susceptibility to a few types of cancers. However, its role in neuroblastoma has not been evaluated yet.

    Tianyou Yang, Zhuorong Zhang, Jiao Zhang, Tianbao Tan, Jiliang Yang, **g Pan… in BMC Cancer (2018)

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  7. Article

    Author Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

    In the version of this Article originally published, the authors incorrectly listed an accession code as GES90642. The correct code is GSE90642. This has now...

    Huilin Huang, Hengyou Weng, Wenju Sun, ** Qin, Hailing Shi… in Nature Cell Biology (2018)

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  8. Article

    Open Access

    Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation

    Higher matrix stiffness affects biological behavior of tumor cells, regulates tumor-associated gene/miRNA expression and stemness characteristic, and contributes to tumor invasion and metastasis. However, the ...

    Sifan Wu, Qiongdan Zheng, **aoxia **ng… in Journal of Experimental & Clinical Cancer … (2018)

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  9. Article

    Open Access

    Decitabine priming prior to low-dose chemotherapy improves patient outcomes in myelodysplastic syndromes-RAEB: a retrospective analysis vs. chemotherapy alone

    The aim of this study was to examine whether decitabine priming prior to low-dose chemotherapeutic regimens could improve outcomes in patients with myelodysplastic syndromes—refractory anemia with excess of bl...

    Li Ye, Yanling Ren, ** Zhou, Chen Mei… in Journal of Cancer Research and Clinical On… (2017)

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