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Article
Open AccessMinimize average tasks processing time in satellite mobile edge computing systems via a deep reinforcement learning method
Recently, the development of Low Earth Orbit (LEO) satellites and the advancement of the Mobile Edge Computing (MEC) paradigm have driven the emergence of the Satellite Mobile Edge Computing (Sat-MEC). Sat-MEC...
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Article
Open AccessA conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience
Cells adapt to cold by increasing levels of unsaturated phospholipids and membrane fluidity through conserved homeostatic mechanisms. Here we report an exceptionally large and evolutionarily conserved protein ...
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Article
Open AccessDCSE:Double-Channel-Siamese-Ensemble model for protein protein interaction prediction
Protein-protein interaction (PPI) is very important for many biochemical processes. Therefore, accurate prediction of PPI can help us better understand the role of proteins in biochemical processes. Although t...
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Article
Open AccessAstrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis
Cholesterols are the main components of myelin, and are mainly synthesized in astrocytes and transported to oligodendrocytes and neurons in the adult brain. It has been reported that Hippo/yes-associated prote...
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Article
Open AccessThe C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex
TMEM132D is a human gene identified with multiple risk alleles for panic disorders, anxiety and major depressive disorders. Defining a conserved family of transmembrane proteins, TMEM132D and its homologs are sti...
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Article
Open AccessTemperature-induced shifts in hibernation behavior in experimental amphibian populations
Phenological shifts are primary responses of species to recent climate change. Such changes might lead to temporal mismatches in food webs and exacerbate species vulnerability. Yet insights into this phenomeno...
