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Article
Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury
Disruption of the blood-spinal cord barrier (BSCB) is a critical event in the secondary injury following spinal cord injury (SCI). Mertk has been reported to play an important role in regulating inflammation a...
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Article
Open AccessMinimize average tasks processing time in satellite mobile edge computing systems via a deep reinforcement learning method
Recently, the development of Low Earth Orbit (LEO) satellites and the advancement of the Mobile Edge Computing (MEC) paradigm have driven the emergence of the Satellite Mobile Edge Computing (Sat-MEC). Sat-MEC...
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Article
Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury
Spinal cord injury (SCI) can lead to the destruction of the blood-spinal cord barrier (BSCB), causing various inflammatory cytokines, neutrophils, and macrophages to infiltrate the lesion area, resulting in se...
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Chapter and Conference Paper
FedDroidADP: An Adaptive Privacy-Preserving Framework for Federated-Learning-Based Android Malware Classification System
Federated-Learning-based Android malware classification framework has attracted much attention due to its privacy-preserving and multi-party joint modeling. However, research shows indirect privacy inferences ...
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Article
Open AccessA conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience
Cells adapt to cold by increasing levels of unsaturated phospholipids and membrane fluidity through conserved homeostatic mechanisms. Here we report an exceptionally large and evolutionarily conserved protein ...
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Article
Open AccessDCSE:Double-Channel-Siamese-Ensemble model for protein protein interaction prediction
Protein-protein interaction (PPI) is very important for many biochemical processes. Therefore, accurate prediction of PPI can help us better understand the role of proteins in biochemical processes. Although t...
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Article
Oxidation-State-Dependent Nonlinear Absorption of Prussian Blue
Research concerning the third-order nonlinear optical (NLO) performance of Prussian blue (PB) is rare. Here, we report the correlation between the oxidation states and the NLO absorption of the PB. Pristine PB...
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Article
Open AccessAstrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis
Cholesterols are the main components of myelin, and are mainly synthesized in astrocytes and transported to oligodendrocytes and neurons in the adult brain. It has been reported that Hippo/yes-associated prote...
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Article
Expansion law and influence factors of hydraulic fracture under the influence of coal pillar
In the process of coal mining, the remaining coal pillars in the overlying strata have a greater impact on the lower mining pressure. Hydraulic fracture can provide a strong control effect, but the crack exten...
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Article
Open AccessThe C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex
TMEM132D is a human gene identified with multiple risk alleles for panic disorders, anxiety and major depressive disorders. Defining a conserved family of transmembrane proteins, TMEM132D and its homologs are sti...
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Article
Open AccessTemperature-induced shifts in hibernation behavior in experimental amphibian populations
Phenological shifts are primary responses of species to recent climate change. Such changes might lead to temporal mismatches in food webs and exacerbate species vulnerability. Yet insights into this phenomeno...
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Article
Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis
The role of the unfolded protein response (UPR) in tissue homeostasis remains largely unknown. Here we find that loss of Mst1/2, the mammalian Hippo orthologues, or their regulator WW45, leads to a remarkably ...
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Article
Isolation of the β-carotene ketolase gene promoter from Haematococcus pluvialis and expression of ble in transgenic Chlamydomonas
The β-carotene ketolase gene (bkt1) is a key enzyme in the biosynthesis of astaxanthin in the green alga Haematococcus pluvialis. We constructed a genomic library of H. pluvialis from which the upstream sequence ...
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Article
Malignant hemangioendothelioma of the Liver: A case report