Skip to main content

and
  1. No Access

    Article

    Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury

    Disruption of the blood-spinal cord barrier (BSCB) is a critical event in the secondary injury following spinal cord injury (SCI). Mertk has been reported to play an important role in regulating inflammation a...

    Jiezhao Lin, Yuanfang Sun, Bin **a, Yihan Wang, Changnan **e in Neuroscience Bulletin (2024)

  2. Article

    Open Access

    Minimize average tasks processing time in satellite mobile edge computing systems via a deep reinforcement learning method

    Recently, the development of Low Earth Orbit (LEO) satellites and the advancement of the Mobile Edge Computing (MEC) paradigm have driven the emergence of the Satellite Mobile Edge Computing (Sat-MEC). Sat-MEC...

    Shanchen Pang, Jianyang Zheng, Min Wang, Sibo Qiao, **ao He in Journal of Cloud Computing (2023)

  3. No Access

    Article

    Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury

    Spinal cord injury (SCI) can lead to the destruction of the blood-spinal cord barrier (BSCB), causing various inflammatory cytokines, neutrophils, and macrophages to infiltrate the lesion area, resulting in se...

    Changnan **e, Yihan Wang, **feng Wang, Yizhou Xu, Haining Liu in Molecular Neurobiology (2023)

  4. No Access

    Chapter and Conference Paper

    FedDroidADP: An Adaptive Privacy-Preserving Framework for Federated-Learning-Based Android Malware Classification System

    Federated-Learning-based Android malware classification framework has attracted much attention due to its privacy-preserving and multi-party joint modeling. However, research shows indirect privacy inferences ...

    Changnan Jiang, Chunhe **a, Zhuodong Liu in Knowledge Science, Engineering and Managem… (2023)

  5. Article

    Open Access

    A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience

    Cells adapt to cold by increasing levels of unsaturated phospholipids and membrane fluidity through conserved homeostatic mechanisms. Here we report an exceptionally large and evolutionarily conserved protein ...

    Changnan Wang, Bingying Wang, Taruna Pandey, Yong Long in Nature Communications (2022)

  6. Article

    Open Access

    DCSE:Double-Channel-Siamese-Ensemble model for protein protein interaction prediction

    Protein-protein interaction (PPI) is very important for many biochemical processes. Therefore, accurate prediction of PPI can help us better understand the role of proteins in biochemical processes. Although t...

    Wenqi Chen, Shuang Wang, Tao Song, Xue Li, Peifu Han, Changnan Gao in BMC Genomics (2022)

  7. No Access

    Article

    Oxidation-State-Dependent Nonlinear Absorption of Prussian Blue

    Research concerning the third-order nonlinear optical (NLO) performance of Prussian blue (PB) is rare. Here, we report the correlation between the oxidation states and the NLO absorption of the PB. Pristine PB...

    Changnan Wu, Hui Li, Yanhui Sun, Ruipeng Hou in Journal of Electronic Materials (2022)

  8. Article

    Open Access

    Astrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis

    Cholesterols are the main components of myelin, and are mainly synthesized in astrocytes and transported to oligodendrocytes and neurons in the adult brain. It has been reported that Hippo/yes-associated prote...

    **g**g Zhang, **ngxing Xu, Huitao Liu, Lingting **, **ya Shen in Cell Death & Disease (2021)

  9. No Access

    Article

    Expansion law and influence factors of hydraulic fracture under the influence of coal pillar

    In the process of coal mining, the remaining coal pillars in the overlying strata have a greater impact on the lower mining pressure. Hydraulic fracture can provide a strong control effect, but the crack exten...

    Binwei **a, Changnan Ou, Xuan Zhang, Yuanhao Fu in Arabian Journal of Geosciences (2021)

  10. Article

    Open Access

    The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex

    TMEM132D is a human gene identified with multiple risk alleles for panic disorders, anxiety and major depressive disorders. Defining a conserved family of transmembrane proteins, TMEM132D and its homologs are sti...

    **n Wang, Wei Jiang, Shuo Luo, **aoyu Yang, Changnan Wang, Bingying Wang in Molecular Brain (2021)

  11. Article

    Open Access

    Temperature-induced shifts in hibernation behavior in experimental amphibian populations

    Phenological shifts are primary responses of species to recent climate change. Such changes might lead to temporal mismatches in food webs and exacerbate species vulnerability. Yet insights into this phenomeno...

    Xu Gao, Changnan **, Diego Llusia, Yiming Li in Scientific Reports (2015)

  12. No Access

    Article

    Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis

    The role of the unfolded protein response (UPR) in tissue homeostasis remains largely unknown. Here we find that loss of Mst1/2, the mammalian Hippo orthologues, or their regulator WW45, leads to a remarkably ...

    Hongtan Wu, Luyao Wei, Fuqin Fan, Suyuan Ji, Shihao Zhang in Nature Communications (2015)

  13. No Access

    Article

    Isolation of the β-carotene ketolase gene promoter from Haematococcus pluvialis and expression of ble in transgenic Chlamydomonas

    The β-carotene ketolase gene (bkt1) is a key enzyme in the biosynthesis of astaxanthin in the green alga Haematococcus pluvialis. We constructed a genomic library of H. pluvialis from which the upstream sequence ...

    Chaogang Wang, Zhangli Hu, Changnan Zhao, **aomo Mao in Journal of Applied Phycology (2012)

  14. No Access

    Article

    Malignant hemangioendothelioma of the Liver: A case report

    Jianjun Lin, Changnan **, Yisheng Zhong in Chinese Journal of Clinical Oncology (2005)