13 Result(s)
within
Chang Su
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessRepurposing non-pharmacological interventions for Alzheimer's disease through link prediction on biomedical literature
Non-pharmaceutical interventions (NPI) have great potential to improve cognitive function but limited investigation to discover NPI repurposing for Alzheimer's Disease (AD). This is the first study to develop ...
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Article
Open AccessAn exposome atlas of serum reveals the risk of chronic diseases in the Chinese population
Although adverse environmental exposures are considered a major cause of chronic diseases, current studies provide limited information on real-world chemical exposures and related risks. For this study, we col...
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Article
Open AccessThe relationship between myodural bridge, atrophy and hyperplasia of the suboccipital musculature, and cerebrospinal fluid dynamics
The Myodural Bridge (MDB) is a physiological structure that is highly conserved in mammals and many of other tetrapods. It connects the suboccipital muscles to the cervical spinal dura mater (SDM) and transmit...
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Open AccessCell-type-specific co-expression inference from single cell RNA-sequencing data
The advancement of single cell RNA-sequencing (scRNA-seq) technology has enabled the direct inference of co-expressions in specific cell types, facilitating our understanding of cell-type-specific biological f...
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Open AccessCandida albicans exploits N-acetylglucosamine as a gut signal to establish the balance between commensalism and pathogenesis
Candida albicans is a benign member of gut microbiota, but also causes life-threatening disseminated infections, suggesting that this fungus commensalism has evolved with retention of virulence traits. Here we re...
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Open AccessHuman reliability assessment of intelligent coal mine hoist system based on Bayesian network
The human reliability of intelligent coal mine hoist operation system is affected by many factors, in order to reduce the occurrence of human error in the hoist system and improve the reliability of the system...
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Open AccessIdentifying organ dysfunction trajectory-based subphenotypes in critically ill patients with COVID-19
COVID-19-associated respiratory failure offers the unprecedented opportunity to evaluate the differential host response to a uniform pathogenic insult. Understanding whether there are distinct subphenotypes of...
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Open AccessAuthor Correction: Effects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
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Article
Open AccessEffects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis
We previously demonstrated that mesenchymal stem cells (MSCs) ameliorated experimental autoimmune uveoretinitis (EAU) in rats. Recently, MSC-derived exosomes (MSC-Exo) were thought to carry functions of MSCs. ...
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Open AccessN-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
N-acetylglucosamine (GlcNAc) exists ubiquitously as a component of the surface on a wide range of cells, from bacteria to humans. Many fungi are able to utilize environmental GlcNAc to support growth and induc...
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Open AccessExosomes derived from MSCs ameliorate retinal laser injury partially by inhibition of MCP-1
Although accumulated evidence supports the notion that mesenchymal stem cells (MSCs) act in a paracrine manner, the mechanisms are still not fully understood. Recently, MSC-derived exosomes (MSC-Exos), a type ...
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Article
Open AccessA fast electrochromic polymer based on TEMPO substituted polytriphenylamine
A novel strategy to obtain rapid electrochromic switching response by introducing 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) moiety into polytriphenylamine backbone has been developed. The electrochromic pro...
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Article
2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity
Improving small interfering RNA (siRNA) efficacy in target cell populations remains a challenge to its clinical implementation. Here, we report a chemical modification, consisting of phosphorodithioate (PS2) a...
