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  1. Article

    Open Access

    Generalizable prediction of childhood ADHD symptoms from neurocognitive testing and youth characteristics

    Childhood attention-deficit/hyperactivity disorder (ADHD) symptoms are believed to result from disrupted neurocognitive development. However, evidence for the clinical and predictive value of neurocognitive as...

    Alexander Weigard, Katherine L. McCurry, Zvi Shapiro in Translational Psychiatry (2023)

  2. Article

    Open Access

    Widespread attenuating changes in brain connectivity associated with the general factor of psychopathology in 9- and 10-year olds

    Convergent research identifies a general factor (“P factor”) that confers transdiagnostic risk for psychopathology. Large-scale networks are key organizational units of the human brain. However, studies of alt...

    Chandra Sripada, Mike Angstadt, Aman Taxali, Daniel Kessler in Translational Psychiatry (2021)

  3. Article

    Open Access

    Brain-wide functional connectivity patterns support general cognitive ability and mediate effects of socioeconomic status in youth

    General cognitive ability (GCA) is an individual difference dimension linked to important academic, occupational, and health-related outcomes and its development is strongly linked to differences in socioecono...

    Chandra Sripada, Mike Angstadt, Aman Taxali, D. Angus Clark in Translational Psychiatry (2021)

  4. No Access

    Article

    Evidence accumulation and associated error-related brain activity as computationally-informed prospective predictors of substance use in emerging adulthood

    Substance use peaks during the developmental period known as emerging adulthood (ages 18–25), but not every individual who uses substances during this period engages in frequent or problematic use. Although in...

    Alexander S. Weigard, Sarah J. Brislin, Lora M. Cope in Psychopharmacology (2021)

  5. No Access

    Article

    Prediction of neurocognition in youth from resting state fMRI

    Difficulties with higher-order cognitive functions in youth are a potentially important vulnerability factor for the emergence of problematic behaviors and a range of psychopathologies. This study examined 201...

    Chandra Sripada, Saige Rutherford, Mike Angstadt in Molecular Psychiatry (2020)

  6. No Access

    Article

    Modeling the effects of methylphenidate on interference and evidence accumulation processes using the conflict linear ballistic accumulator

    Although methylphenidate and other stimulants have been demonstrated to improve task performance across a variety of domains, a computationally rigorous account of how these drugs alter cognitive processing re...

    Alexander Weigard, Andrew Heathcote, Chandra Sripada in Psychopharmacology (2019)

  7. No Access

    Article

    Neuropeptide Y and representation of salience in human nucleus accumbens

    Neuropeptide Y (NPY) produces anxiolytic effects in rodent models, and naturally occurring low NPY expression in humans has been associated with negative emotional phenotypes. Studies in rodent models have als...

    Katherine G. Warthen, Benjamin Sanford, Kendal Walker in Neuropsychopharmacology (2019)