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Article
Open AccessGeneralizable prediction of childhood ADHD symptoms from neurocognitive testing and youth characteristics
Childhood attention-deficit/hyperactivity disorder (ADHD) symptoms are believed to result from disrupted neurocognitive development. However, evidence for the clinical and predictive value of neurocognitive as...
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Article
Open AccessWidespread attenuating changes in brain connectivity associated with the general factor of psychopathology in 9- and 10-year olds
Convergent research identifies a general factor (“P factor”) that confers transdiagnostic risk for psychopathology. Large-scale networks are key organizational units of the human brain. However, studies of alt...
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Article
Open AccessBrain-wide functional connectivity patterns support general cognitive ability and mediate effects of socioeconomic status in youth
General cognitive ability (GCA) is an individual difference dimension linked to important academic, occupational, and health-related outcomes and its development is strongly linked to differences in socioecono...
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Article
Evidence accumulation and associated error-related brain activity as computationally-informed prospective predictors of substance use in emerging adulthood
Substance use peaks during the developmental period known as emerging adulthood (ages 18–25), but not every individual who uses substances during this period engages in frequent or problematic use. Although in...
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Article
Prediction of neurocognition in youth from resting state fMRI
Difficulties with higher-order cognitive functions in youth are a potentially important vulnerability factor for the emergence of problematic behaviors and a range of psychopathologies. This study examined 201...
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Article
Modeling the effects of methylphenidate on interference and evidence accumulation processes using the conflict linear ballistic accumulator
Although methylphenidate and other stimulants have been demonstrated to improve task performance across a variety of domains, a computationally rigorous account of how these drugs alter cognitive processing re...
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Article
Neuropeptide Y and representation of salience in human nucleus accumbens
Neuropeptide Y (NPY) produces anxiolytic effects in rodent models, and naturally occurring low NPY expression in humans has been associated with negative emotional phenotypes. Studies in rodent models have als...