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  1. Article

    Open Access

    A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial

    Patients with difficult-to-control asthma consume 50–60% of healthcare costs attributed to asthma and cost approximately five-times more than patients with mild stable disease. Recent evidence demonstrates tha...

    Catherine E. Hanratty, John G. Matthews, Joseph R. Arron, David F. Choy in Trials (2018)