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    Article

    Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

    An immunotherapy consisting of a tumor-antigen targeting antibody, PD-1 blocking antibody, extended half-life recombinant IL-2 and a lymph-node-targeted T cell vaccine mobilized innate and adaptive immunity an...

    Kelly D Moynihan, Cary F Opel, Gregory L Szeto, Alice Tzeng, Eric F Zhu in Nature Medicine (2016)

  2. Article

    Open Access

    A graphene-based physiometer array for the analysis of single biological cells

    A significant advantage of a graphene biosensor is that it inherently represents a continuum of independent and aligned sensor-units. We demonstrate a nanoscale version of a micro-physiometer – a device that m...

    Geraldine L. C. Paulus, Justin T. Nelson, Katherine Y. Lee in Scientific Reports (2014)

  3. Article

    Open Access

    Combined treatment using adoptive cell therapy, extended pharmacokinetic IL-2, and tumor-specific antibodies leads to cures of established B16F10 tumors and extended in vivo T cell survival

    Cary F Opel, K Dane Wittrup in Journal for ImmunoTherapy of Cancer (2013)