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  1. Article

    Open Access

    CXCL10 is a crucial chemoattractant for efficient intranasal delivery of mesenchymal stem cells to the neonatal hypoxic-ischemic brain

    Hypoxic-Ischemic Encephalopathy (HIE) is a leading cause of mortality and morbidity in newborns. Recent research has shown promise in using intranasal mesenchymal stem cell (MSC) therapy if administered within...

    Eva C. Hermans, Vanessa Donega, Cobi J. Heijnen in Stem Cell Research & Therapy (2024)

  2. No Access

    Article

    The influence of nutrition on white matter development in preterm infants: a sco** review

    White matter (WM) injury is the most common type of brain injury in preterm infants and is associated with impaired neurodevelopmental outcome (NDO). Currently, there are no treatments for WM injury, but optim...

    Els Janson, Marle F. Willemsen, Pauline E. Van Beek, Jeroen Dudink in Pediatric Research (2023)

  3. Article

    Open Access

    Analysing the protection from respiratory tract infections and allergic diseases early in life by human milk components: the PRIMA birth cohort

    Many studies support the protective effect of breastfeeding on respiratory tract infections. Although infant formulas have been developed to provide adequate nutritional solutions, many components in human mil...

    Arthur H. van Stigt, Katrien Oude Rengerink in BMC Infectious Diseases (2022)

  4. Article

    Promoting neuroregeneration after perinatal arterial ischemic stroke: neurotrophic factors and mesenchymal stem cells

    Newborns suffering from perinatal arterial ischemic stroke (PAIS) are at risk of neurodevelopmental problems. Current treatment options for PAIS are limited and mainly focus on supportive care, as presentation...

    Nienke Wagenaar, Caroline G M de Theije, Linda S de Vries in Pediatric Research (2018)

  5. Article

    Open Access

    A quantitative method for microstructural analysis of myelinated axons in the injured rodent brain

    MRI studies (e.g. using diffusion tensor imaging) revealed that injury to white matter tracts, as observed in for instance perinatal white matter injury and multiple sclerosis, leads to compromised microstruct...

    Erik van Tilborg, Caren M. van Kammen, Caroline G. M. de Theije in Scientific Reports (2017)