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Lysosomal Acidification in Cultured Astrocytes Using Nanoparticles

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  1. Article

    Open Access

    High levels of AAV vector integration into CRISPR-induced DNA breaks

    Adeno-associated virus (AAV) vectors have shown promising results in preclinical models, but the genomic consequences of transduction with AAV vectors encoding CRISPR-Cas nucleases is still being examined. In ...

    Killian S. Hanlon, Benjamin P. Kleinstiver, Sara P. Garcia… in Nature Communications (2019)

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  2. Article

    Open Access

    Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells

    In Parkinson’s disease and other Lewy body disorders, the propagation of pathology has been accredited to the spreading of extracellular α-synuclein (α-syn). Although the pathogenic mechanisms are not fully un...

    Gabriel Gustafsson, Camilla Lööv, Emma Persson… in Cellular and Molecular Neurobiology (2018)

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