3 Result(s)
within
Camilla Lööv
Cell Biology
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Article
Open AccessSecretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells
In Parkinson’s disease and other Lewy body disorders, the propagation of pathology has been accredited to the spreading of extracellular α-synuclein (α-syn). Although the pathogenic mechanisms are not fully un...
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Protocol
Lysosomal Acidification in Cultured Astrocytes Using Nanoparticles
Following cellular engulfment, nanoparticles end up in the lysosomes, making them an ideal tool for modifying the lysosomal environment. Here, we describe how acidic nanoparticles can be used to lower the pH o...
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Article
α-Synuclein in Extracellular Vesicles: Functional Implications and Diagnostic Opportunities
Fibrillar inclusions of intraneuronal α-synuclein can be detected in certain brain areas from patients with Parkinson’s disease (PD) and other disorders with Lewy body pathology. These insoluble protein aggreg...
