15 Result(s)

Article

Alcohol consumption in a rural area of Cantabria

A two-stage cross-sectional survey was performed in a representative rural sample of the autonomous community of Cantabria, to investigate the social, medical and psychopathological factors associated with alc...

S. Herrera Castanedo, J. L. Vázquez-Barquero… in Social Psychiatry and Psychiatric Epidemio… (1996)

Article

DICKKOPF-4 is induced by TCF/β-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1α,25-dihydroxyvitamin D₃

Aberrant activation of the Wnt/β-catenin signaling pathway is a hallmark of colon cancer. We show that the Wnt antagonist DICKKOPF-4 (DKK-4) gene is repressed by 1α,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) in human c...

N Pendás-Franco, J M García, C Peña, N Valle, H G Pálmer, M Heinäniemi… in Oncogene (2008)

Article

SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue

SNAI1, ZEB1, E-cadherin (CDH1), and vitamin D receptor (VDR) genes regulate the epithelial–mesenchymal transition (EMT) that initiates the invasion process of many tumor cells. We hypothesized that this process c...

C Peña, J M García, M J Larriba, R Barderas, I Gómez, M Herrera, V García… in Oncogene (2009)

Article

E2f3 in tumor macrophages promotes lung metastasis

The Rb-E2F axis is an important pathway involved in cell-cycle control that is deregulated in a number of cancers. E2f transcription factors have distinct roles in the control of cell proliferation, cell survi...

P Trikha, N Sharma, C Pena, A Reyes, T Pécot, S Khurshid, M Rawahneh, J Moffitt… in Oncogene (2016)

Article

The emerging role of Snail1 in the tumor stroma

The transcription factor Snail1 leads to the epithelial–mesenchymal transition by repressing the adherent and tight junctions in epithelial cells. This process is related to an increase of cell migratory and m...

A. Herrera, M. Herrera, C. Peña in Clinical and Translational Oncology (2016)

Article

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI)

The transcription factor Twist1 is involved in the epithelial–mesenchymal transition and contributes to cancer metastasis through mostly unknown mechanisms. In colorectal cancer, Twist1 expression is mainly re...

I García-Palmero, S Torres, R A Bartolomé, A Peláez-García, M J Larriba… in Oncogene (2016)

Article

Anti-glomerular basement membrane disease due to monoclonal IgG Lambda antibodies: a very rare case of monoclonal gammopathy of renal significance

C. Peña, R. Valjalo, X. Rocca, M. Roa, A. Morales, G. P. Méndez in Annals of Hematology (2019)

Article

Significant differences in access to tests and treatments for multiple myeloma between public and private systems in Latin America. Results of a Latin American survey. GELAMM (Grupo de Estudio Latino Americano de Mieloma Múltiple)

The incidence of multiple myeloma (MM) has increased in the last 20 years, particularly in middle and low-middle income countries. Access to diagnostic and prognostic tests and the availability of effective ca...

Eloísa Riva, N. Schütz, C. Peña, G. Ruiz-Argüelles… in Annals of Hematology (2020)