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Article
Open AccessSTAT1-mediated Bim expression promotes the apoptosis of retinal pericytes under high glucose conditions
Hyperglycemia impacts different vascular cell functions and promotes the development and progression of various vasculopathies including diabetic retinopathy. Although the increased rate of apoptosis in pericy...
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Chapter and Conference Paper
Automated Evaluation of Retinopathies Using Image Cytometry
Retinopathic changes are common to many ocular diseases and if detected early, much of the change caused by various injuries can be prevented or in some cases reversed. However, detection and quantification of...
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Article
Electrochemical Evidence for the Molten Globule States of Cytochrome c Induced by N-Alkyl Sulfates at Low Concentrations
The molten globule state (MG) of cytochrome c is the major intermediate of protein folding. The formation of MG state of cytochrome c is induced by n-alkyl sulfates such as sodium octyl sulfate (SOS), sodium dode...
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Chapter
Mechanisms of Resistance to Platinum Drugs
Development of resistance to cancer chemotherapeutic agents is a major limitation to their clinical use. The phenomenon of resistance was encountered in the first documented case of cancer chemotherapy (1), an...