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  1. Article

    Open Access

    Exploring venlafaxine pharmacokinetic variability with a phenoty** approach, a multicentric french-swiss study (MARVEL study)

    It is well known that the standard doses of a given drug may not have equivalent effects in all patients. To date, the management of depression remains mainly empirical and often poorly evaluated. The developm...

    Célia Lloret-Linares, Youssef Daali, Sylvie Chevret… in BMC Pharmacology and Toxicology (2017)

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    Article

    Effect of a Roux-en-Y Gastric Bypass on the Pharmacokinetics of Oral Morphine Using a Population Approach

    Obesity and opioid use for chronic pain in obese individuals are both important public health concerns. The pharmacokinetics of oral morphine after Roux-en-Y gastric bypass (RYGB) are unknown. Therefore, we ai...

    Célia Lloret-Linares, Déborah Hirt, Christophe Bardin… in Clinical Pharmacokinetics (2014)

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    Article

    Pharmacology of Morphine in Obese Patients

    Morphine is an analgesic drug used to treat acute and chronic pain. Obesity is frequently associated with pain of various origins (e.g. arthritis, fibromyalgia, cancer), which increases the need for analgesic ...

    Célia Lloret Linares, Xavier Decléves, Jean Michel Oppert… in Clinical Pharmacokinetics (2009)