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  1. Article

    An invariant Trypanosoma vivax vaccine antigen induces protective immunity

    Trypanosomes are protozoan parasites that cause infectious diseases, including African trypanosomiasis (slee** sickness) in humans and nagana in economically important livestock1,2. An effective vaccine against...

    Delphine Autheman, Cécile Crosnier, Simon Clare, David A. Goulding in Nature (2021)

  2. No Access

    Protocol

    Cloning of Recombinant Monoclonal Antibodies from Hybridomas in a Single Mammalian Expression Plasmid

    Antibodies are an integral part of biological and medical research. In addition, immunoglobulins are used in many diagnostic tests and are becoming increasingly important in the therapy of diseases. To express...

    Nicole Müller-Sienerth, Cécile Crosnier, Gavin J. Wright in Monoclonal Antibodies (2014)

  3. Article

    Correction: Corrigendum: The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

    Nature Communications 2: Article number: 601 (2011); Published: 20 December 2011; Updated: 19 September 2013. In the Methods section of this Article, the species of the tissue plasminogen activator secretory s...

    Alexander D. Douglas, Andrew R. Williams, Joseph J. Illingworth in Nature Communications (2013)

  4. Article

    The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

    Current vaccine strategies against the asexual blood stage of Plasmodium falciparum are mostly focused on well-studied merozoite antigens that induce immune responses after natural exposure, but have yet to induc...

    Alexander D. Douglas, Andrew R. Williams, Joseph J. Illingworth in Nature Communications (2011)

  5. No Access

    Article

    Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

    The ability to prevent or impair the invasion of erythrocytes by the Plasmodium falciparum merozoite, the initial blood stage of malaria infection, has long been an ambition for those working on antimalarial ther...

    Cécile Crosnier, Leyla Y. Bustamante, S. Josefin Bartholdson, Amy K. Bei in Nature (2011)

  6. Article

    Open Access

    A rapid and scalable method for selecting recombinant mouse monoclonal antibodies

    Monoclonal antibodies with high affinity and selectivity that work on wholemount fixed tissues are valuable reagents to the cell and developmental biologist, and yet isolating them remains a long and unpredict...

    Cécile Crosnier, Nicole Staudt, Gavin J Wright in BMC Biology (2010)

  7. No Access

    Article

    Organizing cell renewal in the intestine: stem cells, signals and combinatorial control

  8. The epithelial lining of the intestine renews itself more rapidly than any other tissue in the vertebrate body, replacing the entire population of differentiat...

  9. Cécile Crosnier, Despina Stamataki, Julian Lewis in Nature Reviews Genetics (2006)

  10. No Access

    Article

    Expression of mutant JAGGED1 alleles in patients with Alagille syndrome

    Heterozygous mutations in JAGGED1 (JAG1), encoding a ligand for Notch receptors, have been identified in patients with Alagille syndrome (AGS). These mutations map to the extracellular and transmembrane domains o...

    Julie Boyer, Cécile Crosnier, Catherine Driancourt, Nicole Raynaud in Human Genetics (2005)