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  1. Article

    Open Access

    Internalization of apoptotic cells during efferocytosis requires Mertk-mediated calcium influx

    Phagocytosis of apoptotic cells, called efferocytosis, requires calcium inside and outside of phagocytes. Due to its necessity, calcium flux is sophisticatedly modulated, and the level of intracellular calcium...

    Susumin Yang, Chanhyuk Min, Hyunji Moon, Byeong** Moon, Juyeon Lee… in Cell Death & Disease (2023)

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  2. Article

    Open Access

    Tim-4 functions as a scavenger receptor for phagocytosis of exogenous particles

    The phosphatidylserine (PS) receptor Tim-4 mediates phagocytosis of apoptotic cells by binding to PS exposed on the surface of these cells, and thus functions as a PS receptor for apoptotic cells. Some of PS r...

    Chanhyuk Min, Jeongjun Park, Gayoung Kim, Hyunji Moon, Sang-Ah Lee… in Cell Death & Disease (2020)

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  3. No Access

    Article

    A scaffold for signaling of Tim-4-mediated efferocytosis is formed by fibronectin

    An essential step during clearance of apoptotic cells is the recognition of phosphatidylserine (PS) exposed on apoptotic cells by its receptors on phagocytes. Tim-4 directly binding to PS and functioning as a ...

    Juyeon Lee, Boyeon Park, Byeong** Moon, Jeongjun Park… in Cell Death & Differentiation (2019)