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Article
DANAZOL-INDUCED FACTOR IX AND VIII BYPASSING ACTIVITY
Danazol, a synthetic androgen reported to increase factor VIII and IX activity levels, was given to 5 hemophiliacs who were >17 years old (3 with severe hemophilia A, one moderate hemophilia A and one moderate...
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Article
EFFECT OF DANAZOL ON APTT, COAGULANT FACTOR ACTIVITY AND BLEEDING IN HEMOPHILIA
Danazol has been reported to raise several plasma proteins. Danazol was given orally at 600 mg/day in 3 divided doses to 6 hemophiliacs for 8-14 weeks. Factor levels, APTT and other laboratory parameters were ...
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Article
Altered Polyamine Metabolism in Cystic Fibrosis
Summary: Children with cystic fibrosis excreted elevated urinary levels of all three polyamines—putrescine, spermidine, and spermine. Heterozygote parents excreted intermediate concentrations of the polyamines...