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Mepirapim, a novel synthetic cannabinoid, induces Parkinson’s disease-related behaviors by causing maladaptation of the dopamine system in the brain
Mepirapim is a novel synthetic cannabinoid that first appeared on the illicit drug market in 2013. In recent years, recreational abuse of Mepirapim has caused serious emergencies, posing a threat to public hea...
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Article
Correction to: New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents
Unfortunately, original publication of the article has been published with an error in author contribution. The following phrase is added for correction.
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Article
New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents
2C (2C-x) is the general name for the family of phenethylamines containing two methoxy groups at the 2 and 5 positions of the benzene ring. The abuse of 2C family drugs has grown rapidly, although the abuse po...
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Article
Effect of nifedipine, a calcium channel blocker, on the generation of nitric oxide and interleukin-1β by murine macrophages activated by lipopolysaccharide from Prevotella intermedia
Nifedipine, a calcium channel blocker, has been reported to possess anti-inflammatory and immunosuppressive effects. The current study was undertaken to explore the influence of nifedipine on the generation of...
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Article
Correction to: Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats
The authors have noted an error in Fig. 1B and Fig. 1C.
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Article
Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats
Drug use during adolescence results in a lifelong risk to develop substance-use disorders. Adolescent rats are less reactive to cocaine-associated cues compared with adults; however, the contribution of adoles...
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Article
25C-NBF, a new psychoactive substance, has addictive and neurotoxic potential in rodents
The use of new psychoactive substances (NPSs) as a substitute for illegal drugs is increasing rapidly and is a serious threat to public health. 25C-NBF is a newly synthesized phenethylamine-type NPS that acts ...
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Article
Tablet Formulation of a Polymeric Solid Dispersion Containing Amorphous Alkalinized Telmisartan
To overcome the poor dissolution of telmisartan (TMS) at weak acidic pH, amorphous alkalinized TMS (AAT) was prepared by introducing sodium hydroxide as a selective alkalizer. AAT-containing polymeric solid di...
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Article
Phentermine induces conditioned rewarding effects via activation of the PI3K/Akt signaling pathway in the nucleus accumbens
Phentermine is structurally similar to methamphetamine and is widely used as an anti-obesity drug in the USA and many other countries. The potential for reward of phentermine has been noted; however, the mecha...