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    Mepirapim, a novel synthetic cannabinoid, induces Parkinson’s disease-related behaviors by causing maladaptation of the dopamine system in the brain

    Mepirapim is a novel synthetic cannabinoid that first appeared on the illicit drug market in 2013. In recent years, recreational abuse of Mepirapim has caused serious emergencies, posing a threat to public hea...

    Kwang-Hyun Hur, Youyoung Lee, Audrey Lynn Donio, Jae-Gyeong Lee in Archives of Toxicology (2023)

  2. Article

    Correction to: New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents

    Unfortunately, original publication of the article has been published with an error in author contribution. The following phrase is added for correction.

    Young-Jung Kim, Shi-Xun Ma, Kwang-Hyun Hur, Youyoung Lee in Archives of Toxicology (2021)

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    New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents

    2C (2C-x) is the general name for the family of phenethylamines containing two methoxy groups at the 2 and 5 positions of the benzene ring. The abuse of 2C family drugs has grown rapidly, although the abuse po...

    Young-Jung Kim, Shi-Xun Ma, Kwang-Hyun Hur, Youyoung Lee in Archives of Toxicology (2021)

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    Effect of nifedipine, a calcium channel blocker, on the generation of nitric oxide and interleukin-1β by murine macrophages activated by lipopolysaccharide from Prevotella intermedia

    Nifedipine, a calcium channel blocker, has been reported to possess anti-inflammatory and immunosuppressive effects. The current study was undertaken to explore the influence of nifedipine on the generation of...

    So-Hui Choe, Eun-Young Choi, **-Yi Hyeon in Naunyn-Schmiedeberg's Archives of Pharmaco… (2021)

  5. Article

    Correction to: Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats

    The authors have noted an error in Fig. 1B and Fig. 1C.

    Bo Ram Cho, Jennifer Gerena, Doris I. Olekanma, Aneesh Bal in Psychopharmacology (2020)

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    Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats

    Drug use during adolescence results in a lifelong risk to develop substance-use disorders. Adolescent rats are less reactive to cocaine-associated cues compared with adults; however, the contribution of adoles...

    Bo Ram Cho, Jennifer Gerena, Doris I. Olekanma, Aneesh Bal in Psychopharmacology (2020)

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    25C-NBF, a new psychoactive substance, has addictive and neurotoxic potential in rodents

    The use of new psychoactive substances (NPSs) as a substitute for illegal drugs is increasing rapidly and is a serious threat to public health. 25C-NBF is a newly synthesized phenethylamine-type NPS that acts ...

    Kwang-Hyun Hur, Seong-Eon Kim, Bo-Ram Lee, Yong-Hyun Ko in Archives of Toxicology (2020)

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    Tablet Formulation of a Polymeric Solid Dispersion Containing Amorphous Alkalinized Telmisartan

    To overcome the poor dissolution of telmisartan (TMS) at weak acidic pH, amorphous alkalinized TMS (AAT) was prepared by introducing sodium hydroxide as a selective alkalizer. AAT-containing polymeric solid di...

    Jun Soo Chae, Bo Ram Chae, Dong Jun Shin, Yoon Tae Goo, Eun Seok Lee in AAPS PharmSciTech (2018)

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    Phentermine induces conditioned rewarding effects via activation of the PI3K/Akt signaling pathway in the nucleus accumbens

    Phentermine is structurally similar to methamphetamine and is widely used as an anti-obesity drug in the USA and many other countries. The potential for reward of phentermine has been noted; however, the mecha...

    Sa-Ik Hong, Min-Jung Kim, In-Jee You, Seung-Hwan Kwon, Shi-Xun Ma in Psychopharmacology (2016)