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Open AccessTargeted inhibition of tumor-derived exosomes as a novel therapeutic option for cancer
Mounting evidence indicates that tumor-derived exosomes (TDEs) play critical roles in tumor development and progression by regulating components in the tumor microenvironment (TME) in an autocrine or paracrine...
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Article
Open AccessMutation of IPO13 causes recessive ocular coloboma, microphthalmia, and cataract
Ocular coloboma is a developmental structural defect of the eye that often occurs as complex ocular anomalies. However, its genetic etiology remains largely unexplored. Here we report the identification of mut...