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Article
Open AccessExpression of microRNA in human retinal pigment epithelial cells following infection with Zaire ebolavirus
Survivors of Ebola virus disease (EVD) are at risk of develo** blinding intraocular inflammation—or uveitis—which is associated with retinal pigment epithelial (RPE) scarring and persistence of live Zaire ebola...
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Article
Open AccessICAM-1-related long non-coding RNA: promoter analysis and expression in human retinal endothelial cells
Regulation of intercellular adhesion molecule (ICAM)-1 in retinal endothelial cells is a promising druggable target for retinal vascular diseases. The ICAM-1-related (ICR) long non-coding RNA stabilizes ICAM-1...
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Article
Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts
Myotonic dystrophy (DM) is an autosomal dominant disorder characterized by skeletal muscle wasting, myotonia, cardiac arrhythmia, hyperinsulinaemia, mental retardation and ocular cataracts1. The genetic defect in...