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  1. Article

    Open Access

    Efficacy and safety of self-made covered coronary stent in the treatment of coronary artery perforation

    To observe the efficacy and safety of self-made covered coronary stent in the treatment of coronary artery perforation.

    Wen An, Jian Ye, Bingyu Han, Xu Wang, Chao Han, Junqing Gao in BMC Cardiovascular Disorders (2023)

  2. Article

    Open Access

    Neo-intline: integrated pipeline enables neoantigen design through the in-silico presentation of T-cell epitope

    Neoantigen vaccines are one of the most effective immunotherapies for personalized tumour treatment. The current immunogen design of neoantigen vaccines is usually based on whole-genome sequencing (WGS) and bi...

    Bingyu Li, ** **g, Genhui Zheng, Chenyu Pi in Signal Transduction and Targeted Therapy (2023)

  3. Article

    Open Access

    Identification and experimental validation of autophagy-related genes in abdominal aortic aneurysm

    Autophagy plays essential roles in abdominal aortic aneurysm (AAA) development and progression. The objective of this study was to verify the autophagy-related genes (ARGs) underlying AAA empirically and using...

    **aoli Yuan, Yancheng Song, Hai **n, Lu Zhang in European Journal of Medical Research (2023)

  4. Article

    Open Access

    The prognostic study of mental stress-induced myocardial ischemia in coronary revascularization patients with depression/anxiety: rationale and design

    Mental stress-induced myocardial ischemia (MSIMI) frequently occurs in patients with coronary artery disease (CAD), and is even more common in patients with co-occurring CAD and depression/anxiety. MSIMI appea...

    Nan Nan, Lei Feng, Wei Dong, Bingyu Gao, Huijuan Zuo in BMC Cardiovascular Disorders (2023)

  5. Article

    Open Access

    Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease

    Interleukin 27 (IL-27), a heterodimeric cytokine composed of Epstein-Barr virus-induced 3 and p28, is a pleiotropic cytokine with both pro-and anti-inflammatory properties. However, the precise role of IL-27 i...

    Huanle Gong, Shoubao Ma, Jia Chen, Bingyu Yang in Signal Transduction and Targeted Therapy (2022)

  6. Article

    Open Access

    Clinical value and role of microRNA-29c-3p in sepsis-induced inflammation and cardiac dysfunction

    The goal of this study was to investigate the diagnostic value of miR-29c-3p in sepsis and its role in sepsis-induced inflammatory response and cardiac dysfunction.

    Bingyu Zhang, Lin Yu, Ying Sheng in European Journal of Medical Research (2021)

  7. Article

    Open Access

    TRIM31 facilitates K27-linked polyubiquitination of SYK to regulate antifungal immunity

    Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase, which plays an essential role in both innate and adaptive immunity. However, the key molecular mechanisms that regulate SYK activity are poorly u...

    Xueer Wang, Honghai Zhang, Zhugui Shao in Signal Transduction and Targeted Therapy (2021)

  8. Article

    Open Access

    High stearic acid diet modulates gut microbiota and aggravates acute graft-versus-host disease

    Bingyu Yang, **anfeng Zhang, Huanle Gong in Signal Transduction and Targeted Therapy (2021)