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Open AccessEffectiveness of human immunodeficiency virus prevention strategies by map** the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China
The Guangxi government initiated two rounds of the Guangxi AIDS Conquering Project (GACP) in 2010 (Phase I) and 2015 (Phase II) to control human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome ...
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Article
Open AccessEfficacy and safety of self-made covered coronary stent in the treatment of coronary artery perforation
To observe the efficacy and safety of self-made covered coronary stent in the treatment of coronary artery perforation.
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Open AccessNeo-intline: integrated pipeline enables neoantigen design through the in-silico presentation of T-cell epitope
Neoantigen vaccines are one of the most effective immunotherapies for personalized tumour treatment. The current immunogen design of neoantigen vaccines is usually based on whole-genome sequencing (WGS) and bi...
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Article
Open AccessIdentification and experimental validation of autophagy-related genes in abdominal aortic aneurysm
Autophagy plays essential roles in abdominal aortic aneurysm (AAA) development and progression. The objective of this study was to verify the autophagy-related genes (ARGs) underlying AAA empirically and using...
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Article
Open AccessUptake of HIV testing and its correlates among sexually experienced college students in Southwestern, China: a Web-Based online cross-sectional study
The prevalence of human immunodeficiency virus (HIV) is becoming more common among college students in China. However, latest data on the prevalence and correlates of HIV testing among sexually experienced col...
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Open AccessThe prognostic study of mental stress-induced myocardial ischemia in coronary revascularization patients with depression/anxiety: rationale and design
Mental stress-induced myocardial ischemia (MSIMI) frequently occurs in patients with coronary artery disease (CAD), and is even more common in patients with co-occurring CAD and depression/anxiety. MSIMI appea...
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Open AccessDendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease
Interleukin 27 (IL-27), a heterodimeric cytokine composed of Epstein-Barr virus-induced 3 and p28, is a pleiotropic cytokine with both pro-and anti-inflammatory properties. However, the precise role of IL-27 i...
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Open AccessHigh-flow nasal cannula oxygen therapy versus noninvasive ventilation for patients with blunt chest trauma: protocol for a randomized controlled trial
High-flow nasal cannula oxygen therapy (HFNC) is recommended by some scholars as an optimized respiratory support method for blunt chest trauma (BCT) patients. The basis of this recommendation is limited, howe...
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Open AccessClinical value and role of microRNA-29c-3p in sepsis-induced inflammation and cardiac dysfunction
The goal of this study was to investigate the diagnostic value of miR-29c-3p in sepsis and its role in sepsis-induced inflammatory response and cardiac dysfunction.
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Open AccessTRIM31 facilitates K27-linked polyubiquitination of SYK to regulate antifungal immunity
Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase, which plays an essential role in both innate and adaptive immunity. However, the key molecular mechanisms that regulate SYK activity are poorly u...
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Open AccessHigh stearic acid diet modulates gut microbiota and aggravates acute graft-versus-host disease
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Open AccessLong-term ozone exposures and cause-specific mortality in a US Medicare cohort
We examined the association of long-term, daily 1-h maximum O3 (ozone) exposures on cause-specific mortality for 22.2 million US Medicare beneficiaries between 2000–2008. We modeled the association between O3 and...
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Open AccessHIV prevalence among female sex workers in Guigang City, Guangxi, China: an 8-year consecutive cross-sectional study
Female sex workers (FSW) are a population that are at high risk for HIV infection, and their HIV/AIDS knowledge levels and sexual behaviors are of concern. This study describes changes in HIV prevalence and fa...
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Internal auditory canal cisternography: report of 27 cases
Small acoustic neuromas, especially when located within the internal auditory canal (IAC), are difficult to be detected by ordinary X-ray methods. We prefer using small dose Myodil IAC cisternography, with whi...