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Article
Olfactory Dysfunction in Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) is a prevalent and heterogeneous inflammatory disease that affects millions of people worldwide. Olfactory dysfunction (OD) is one of the most common symptoms of CRS patients. Incr...
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Article
Open AccessConstruction and validation of a nomogram for predicting survival in elderly patients with severe acute pancreatitis: a retrospective study from a tertiary center
There is a lack of adequate models specifically designed for elderly patients with severe acute pancreatitis (SAP) to predict the risk of death. This study aimed to develop a nomogram for predicting the overal...
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Article
Prevalence, Trends and Correlates of HIV, Syphilis and HCV Infection Among Chinese Local and Cross-border Migrant Female Sex Workers in the Sino-Vietnam Border Area of Guangxi, 2016–2021
Female sex workers (FSWs) are considered a high-risk group for sexually transmitted infections (STIs). However, limited data exist on the prevalence and trends of HIV, syphilis and HCV among FSWs in the Sino-V...
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Article
Open AccessEffectiveness of human immunodeficiency virus prevention strategies by map** the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China
The Guangxi government initiated two rounds of the Guangxi AIDS Conquering Project (GACP) in 2010 (Phase I) and 2015 (Phase II) to control human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome ...
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Article
Open AccessIntegrating molecular subtype and CD8+ T cells infiltration to predict treatment response and survival in muscle-invasive bladder cancer
Luminal and Basal are the primary intrinsic subtypes of muscle-invasive bladder cancer (MIBC). The presence of CD8+ T cells infiltration holds significant immunological relevance, potentially influencing the effi...
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Article
Open AccessThe origin, dissemination, and molecular networks of HIV-1 CRF65_cpx strain in Hainan Island, China
HIV-1 CRF65_cpx strain carries drug-resistant mutations, which raises concerns about its potential for causing virologic failure. The CRF65_cpx ranks as the fourth most prevalent on Hainan Island, China. Howev...
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Article
Open AccessStatus and related factors of professional growth among young nursing talents: a cross-sectional study in China
The shortage of nurses has been a global human resources problem. A good professional growth environment is essential to develo** potential nursing students and attracting nurses to join, and it has great si...
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Article
Open AccessThe value of the first postoperative diagnostic I-131 scan in patients with papillary thyroid carcinoma
To explore the feasibility of the postoperative diagnostic 131I whole-body planar scans (Dx-WBS) in papillary thyroid cancer (PTC) patients, and to clarify its value for accurate staging, risk stratification, and...
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Article
Open AccessAn analysis of differences in Carbapenem-resistant Enterobacterales in different regions: a multicenter cross-sectional study
This study aimed to explore the characteristics of carbapenem-resistant Enterobacterales (CRE) patients in the intensive care unit (ICU) in different regions of Henan Province to provide evidence for the targeted...
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Article
Voxel-wise map** of DCE-MRI time-intensity-curve profiles enables visualizing and quantifying hemodynamic heterogeneity in breast lesions
To propose a novel model-free data-driven approach based on the voxel-wise map** of DCE-MRI time-intensity-curve (TIC) profiles for quantifying and visualizing hemodynamic heterogeneity and to validate its p...
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Article
Open AccessEffect of transcutaneous electrical acupoint stimulation on remifentanil dosage during craniotomy aneurysm clip**: a prospective, randomized controlled study
Craniotomy aneurysm clip** is one of the main treatments for intracranial aneurysm (IA). Endotracheal intubation and intraoperative operation may induce dramatic hemodynamic fluctuations and increase the ris...
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Article
Open AccessParametric and non-parametric Poisson regression for modelling of the arterial input function in positron emission tomography
Full quantification of Positron Emission Tomography (PET) requires an arterial input function (AIF) for measurement of certain targets, or using particular radiotracers, or for the quantification of specific o...
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Article
Open AccessEfficacy and safety of self-made covered coronary stent in the treatment of coronary artery perforation
To observe the efficacy and safety of self-made covered coronary stent in the treatment of coronary artery perforation.
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Article
Open AccessNeo-intline: integrated pipeline enables neoantigen design through the in-silico presentation of T-cell epitope
Neoantigen vaccines are one of the most effective immunotherapies for personalized tumour treatment. The current immunogen design of neoantigen vaccines is usually based on whole-genome sequencing (WGS) and bi...
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Article
Open AccessIdentification and experimental validation of autophagy-related genes in abdominal aortic aneurysm
Autophagy plays essential roles in abdominal aortic aneurysm (AAA) development and progression. The objective of this study was to verify the autophagy-related genes (ARGs) underlying AAA empirically and using...
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Article
Open AccessUptake of HIV testing and its correlates among sexually experienced college students in Southwestern, China: a Web-Based online cross-sectional study
The prevalence of human immunodeficiency virus (HIV) is becoming more common among college students in China. However, latest data on the prevalence and correlates of HIV testing among sexually experienced col...
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Article
Open AccessTrends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020)
Data on recent human immunodeficiency virus (HIV), hepatitis C virus (HCV) and syphilis prevalence among drug users in the Southwest China are sparse despite the high burden of drug use. This study aims at ass...
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Article
Open AccessThe prognostic study of mental stress-induced myocardial ischemia in coronary revascularization patients with depression/anxiety: rationale and design
Mental stress-induced myocardial ischemia (MSIMI) frequently occurs in patients with coronary artery disease (CAD), and is even more common in patients with co-occurring CAD and depression/anxiety. MSIMI appea...
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Article
ASO Visual Abstract: Survival Outcomes of Sublobectomy and Lobectomy in Elderly Patients with Peripheral Solid-Dominant Non-Small Cell Lung Cancer
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Article
Survival Outcomes of Sublobectomy and Lobectomy in Elderly Patients with Peripheral Solid-Dominant Non-small Cell Lung Cancer
According to the JCOG0802 study, there were many non-cancer-related deaths in the lobectomy group. Meanwhile, the median age of the enrolled patients in the JCOG0802 study was 67 years old. Whether this differ...