7 Result(s)
within
English
Life Sciences
Cell Biology
Stem Cells
Bingyu **g
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Article
Open AccessExosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure
Human menstrual blood-derived stem cells (MenSCs) are a novel source of MSCs that provide the advantage of being easy to collect and isolate. Exosomes contain some mRNAs and adhesion molecules that can potenti...
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Article
Open AccessMesenchymal stem cell transplantation ameliorates Sjögren’s syndrome via suppressing IL-12 production by dendritic cells
Mesenchymal stem cells (MSCs) have been demonstrated to be effective in treating autoimmune diseases including Sjögren’s syndrome (SS). We aim to compare the effects of MSC transplantation (MSCT) and the role ...
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Article
Open AccessSatb2 is required for the regionalization of retrosplenial cortex
The retrosplenial cortex (Rsp) is a transitional cortex located between the neocortex and archicortex, but the molecular mechanism specifying Rsp from the archicortex remains elusive. We here report that the t...
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Article
Open AccessNonwoven-based gelatin/polycaprolactone membrane loaded with ERK inhibitor U0126 for treatment of tendon defects
Tendon is a major component of musculoskeletal system connecting the muscles to the bone. Tendon injuries are very common orthopedics problems leading to impeded motion. Up to now, there still lacks effective ...
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Article
Open AccessKnockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA
N6-methyladenosine (m6A) is abundant in the mammalian brain and is considered to have a wide range of effects on learning and memory. Here, we found that the upregulated methyltransferase-like protein 16 (METTL16...
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Article
CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity
cGAS/DncV-like nucleotidyltransferase (CD-NTase) family members are immune sensors that synthesize diverse nucleotide signals to initiate antiviral response in bacteria and animals. As a founding member of CD-...
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Article
Open AccessOTUD5 promotes the inflammatory immune response by enhancing MyD88 oligomerization and Myddosome formation
Myddosome is an oligomeric complex required for the transmission of inflammatory signals from TLR/IL1Rs and consists of MyD88 and IRAK family kinases. However, the molecular basis for the self-assemble of Mydd...
