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    NFκB-sensitive Orai1 expression in the regulation of FGF23 release

    Fibroblast growth factor (FGF23) plasma levels are elevated in cardiac and renal failure and correlate with poor clinical prognosis of those disorders. Both disorders are associated with inflammation and activ...

    Bingbing Zhang, **g Yan, Anja T. Umbach, Hajar Fakhri in Journal of Molecular Medicine (2016)

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    Checkpoint kinase Chk2 controls renal Cyp27b1 expression, calcitriol formation, and calcium-phosphate metabolism

    Checkpoint kinase 2 (Chk2) is the main effector kinase of ataxia telangiectasia mutated (ATM) and responsible for cell cycle regulation. ATM signaling has been shown to upregulate interferon-regulating factor-...

    Hajar Fahkri, Bingbing Zhang, Abul Fajol in Pflügers Archiv - European Journal of Phys… (2015)

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    Regulation of mineral metabolism by lithium

    Lithium, an inhibitor of glycogen synthase kinase 3 (GSK3), is widely used for the treatment of mood disorders. Side effects of lithium include nephrogenic diabetes insipidus, leading to renal water loss. Dehy...

    Hajar Fakhri, Ganesh Pathare, Abul Fajol in Pflügers Archiv - European Journal of Phys… (2014)

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    Contrasting expression of membrane metalloproteinases, MT1-MMP and MT3-MMP, suggests distinct functions in skeletal development

    Membrane-type 1 matrix metalloproteinase (MT1-MMP) is the most ubiquitous and widely studied of the membrane-type metalloproteinases (MT-MMPs). It was thus surprising to find no published data on chicken MT1-M...

    Maozhou Yang, Bingbing Zhang, Liang Zhang, Gary Gibson in Cell and Tissue Research (2008)