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Article
Regulation of cell differentiation to promote pullulan synthesis in Aureobasidium pullulans NG
Pullulan is a polymer produced by Aureobasidium spp. The yield of pullulan production can be impacted by the cellular differentiation of Aureobasidium spp., which changes with alterations in the growth environmen...
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Article
Simultaneous Extraction of Flavonoid Glycosides and Flavonoid Aglycones from Discarded Apple Branches by Enzyme-assisted Micelle-mediated Extraction with Cloud Point Enrichment Method
Extraction of flavonoid glycosides and flavonoid aglycones simultaneously by enzyme-assisted micelle-mediated extraction has been proposed in this study. The discarded apple tree branches pruned during winter ...
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Reference Work Entry In depth
Extracellular Vesicle-Mediated CRISPR/Cas Delivery: Their Applications in Molecular Imaging and Precision Biomedicine
In this book chapter, we provide a comprehensive overview of the latest breakthroughs of delivery systems of CRISPR-Cas via extracellular vesicles (EVs) towards precise therapeutics and diagnosis. Typically, r...
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Living Reference Work Entry In depth
Extracellular Vesicle-Mediated CRISPR/Cas Delivery: Their Applications in Molecular Imaging and Precision Biomedicine
In this book chapter, we provide a comprehensive overview of the latest breakthroughs of delivery systems of CRISPR-Cas via extracellular vesicles (EVs) towards precise therapeutics and diagnosis. Typically, r...
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Article
Long Non-coding RNA TPT1-AS1 Suppresses APC Transcription in a STAT1-Dependent Manner to Increase the Stemness of Colorectal Cancer Stem Cells
Cancer stem cells (CSCs) are the major culprits leading to a new level of complexity and the consequential therapy resistance and disease recurrence in colorectal cancer (CRC). This study focuses on the effect...
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Article
The construction of a dual-functional strain that produces both polysaccharides and sulfotransferases
Heparosan is used as the starting polysaccharide sulfated using sulfotransferase to generate fully elaborate heparin, a widely used clinical drug. However, the preparation of heparosan and enzymes was consider...
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Article
Metabolomics integrated with transcriptomics: assessing the central metabolism of marine red yeast Sporobolomyces pararoseus under salinity stress
Salinity stress is one of the most serious environmental issues in agricultural regions worldwide. Excess salinity inhibits root growth of various crops, and results in reductions of yield. It is of crucial to...
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Article
Heparin stimulates biofilm formation of Escherichia coli strain Nissle 1917
Escherichia coli strain Nissle 1917 (EcN), a gut probiotic competing with pathogenic bacteria, has been used to attenuate various intestinal dysfunctions. Heparin is a sulfated glycosaminoglycan enriched in the h...
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Article
Enzymatic Synthesis of Lipophilic Caffeoyl Lipids Using Soybean Oil as the Novel Acceptor
Soybean oil-based caffeoyl lipids are the novel lipophilic derivatives of caffeic acid, which can be used as UV absorbers and antioxidants in the food and cosmetic industries. In the work, the novel lipophilic...
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Article
Open AccessA novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea
Marine microbes are a large and diverse group, which are exposed to a wide variety of pressure, temperature, salinity, nutrient availability and other environmental conditions. They provide a huge potential so...
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Article
An Improved Method of Gene Synthesis Based on DNA Works Software and Overlap Extension PCR
A bottleneck in recent gene synthesis technologies is the high cost of oligonucleotide synthesis and post-synthesis sequencing. In this article, a simple and rapid method for low-cost gene synthesis technology...