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Article
The construction of a dual-functional strain that produces both polysaccharides and sulfotransferases
Heparosan is used as the starting polysaccharide sulfated using sulfotransferase to generate fully elaborate heparin, a widely used clinical drug. However, the preparation of heparosan and enzymes was consider...
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Article
Heparin stimulates biofilm formation of Escherichia coli strain Nissle 1917
Escherichia coli strain Nissle 1917 (EcN), a gut probiotic competing with pathogenic bacteria, has been used to attenuate various intestinal dysfunctions. Heparin is a sulfated glycosaminoglycan enriched in the h...
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Article
Open AccessA novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea
Marine microbes are a large and diverse group, which are exposed to a wide variety of pressure, temperature, salinity, nutrient availability and other environmental conditions. They provide a huge potential so...