8 Result(s)
within
BingHan **
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessChemotherapy-induced high expression of IL23A enhances efficacy of anti-PD-1 therapy in TNBC by co-activating the PI3K-AKT signaling pathway of CTLs
Treatment of advanced triple-negative breast cancer (TNBC) is a great challenge in clinical practice. The immune checkpoints are a category of immunosuppressive molecules that cancer could hijack and impede an...
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Article
Open AccessMicrobial imbalance in Chinese children with diarrhea or constipation
Diarrhea and constipation are common health concerns in children. Numerous studies have identified strong association between gut microbiota and digestive-related diseases. But little is known about the gut mi...
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Article
Open AccessUniversal Murray’s law for optimised fluid transport in synthetic structures
Materials following Murray’s law are of significant interest due to their unique porous structure and optimal mass transfer ability. However, it is challenging to construct such biomimetic hierarchical channel...
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Article
Open AccessUnravelling and reconstructing the biosynthetic pathway of bergenin
Bergenin, a rare C-glycoside of 4-O-methyl gallic acid with pharmacological properties of antitussive and expectorant, is widely used in clinics to treat chronic tracheitis in China. However, its low abundance in...
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Article
Open AccessTwo orthogonal differentiation gradients locally coordinate fruit morphogenesis
Morphogenesis requires the coordination of cellular behaviors along developmental axes. In plants, gradients of growth and differentiation are typically established along a single longitudinal primordium axis ...
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Article
Open AccessLifestyle patterns influence the composition of the gut microbiome in a healthy Chinese population
High-throughput sequencing allows for the comprehensive analysis of the human intestinal microbiota. However, extensive association analyses between the microbiome and lifestyle differences in the Chinese popu...
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Article
Open AccessStudy on hyperspectral estimation model of soil organic carbon content in the wheat field under different water treatments
Hyperspectral remote sensing technology can be used to monitor the soil nutrient changes in a rapid, real-time, and non-destructive manner, which is of great significance to promote the development of precisio...
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Article
Open AccessCatalytic preparation of levulinic acid from cellobiose via Brønsted-Lewis acidic ionic liquids functional catalysts
Brønsted-Lewis acidic ionic liquids (ILs) were applied to catalyze cellobiose to prepare levulinic acid (LA) in one pot under hydrothermal conditions. Under the optimum conditions, the highest LA yield of 67.5...
